Recombinant human BMF protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Bcl2 modifying factor, also known as BMF belongs to the Bcl2 protein family of apoptosis mediators. Bmf is constitutively expressed in many tissues. This protein contains a single Bcl2 homology domain 3 (BH3), and has been shown to bind Bcl2 proteins and function as an apoptotic activator. Also, BMF is a key molecule for histone deacetylase (HDAC) inhibitors which alters the balance between acetylation and deacetylation, significantly increasing histone acetylation, while strongly inducing apoptosis in a variety of cancer cell types. Recombinant human BMF, fused to T7-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing, 1mM DTT, 10% glycerol

Cancer

< 1 EU per 1ug of protein (determined by LAL method)

BMF, Bcl2 modifying factor isoform 3, Bcl2 modifying factor, isoform 3, BMF, Bcl2 modifying factor, isoform 3 Bcl 2 modifying factor, FLJ00065., ATGP0324-10ug, ATGP0324-20ug, ATGP0324-50ug, ATGP0324-100ug, ATGP0324-250ug, ATGP0324-500ug, ATGP0324-1mg, ATGP0324-10, ATGP0324-20, ATGP0324-50, ATGP0324-100, ATGP0324-250, ATGP0324-500, ATGP0324-1