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Recombinant human Carbonic Anhydrase 2/CA2 protein

Recombinant human Carbonic Anhydrase 2/CA2 protein

Item no.	NKM-ATGP0325-20ug
Manufacturer	NKMAX
Amount	20 ug
Quantity options	100 ug 20 ug 500 ug
Category	Neuroscience Metabolism Diabetes Molecular Targets for Neuroscience Peptides & Proteins Recombinant Proteins SDS-PAGE
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	Untagged
Purity	> 95% by SDS-PAGE
Sequence	MSHHWGYGKH NGPEHWHKDF PIAKGERQSP VDIDTHTAKY DPSLKPLSVS YDQATSLRIL NNGHAFNVEF DDSQDKAVLK GGPLDGTYRL IQFHFHWGSL DGQGSEHTVD KKKYAAELHL VHWNTKYGDF GKAVQQPDGL AVLGIFLKVG SAKPGLQKVV DVLDSIKTKG KSADFTNFDP RGLLPESLDY WTYPGSLTTP PLLECVTWIV LKEPISVSSE QVLKFRKLNF NG
Citations	Hu PY., et al. (1992). Hum Mutat. 1(4):288-92 Venta PJ., et al. (1991). Am J Hum Genet. 49(5):1082-90 Saito M, et al. A case of paraneoplastic optic neuropathy and outer retinitis positive for autoantibodies against collapsin response mediator protein-5, recoverin, and α-enolase. (BMC Ophthalmol. 2014){https://pubmed.ncbi.nlm.nih.gov/24428923/}
NCBI	NP_000058.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Carbonic anhydrase II,CA-II,Carbonate dehydratase II,Carbonic anhydrase C,CAC,Cyanamide hydratase CA2,Car2
Similar products	CA2, Carbonic anhydrase B, CAC, CA-II, Car2, CA II, Carbonic Anhydrase II, Carbonic anhydrase 2, CAI, CA 2, Car 2, Carbonate dehydratase II, Carbonic anhydrase C, Carbonic anhydrase II, Carbonic dehydratase., ATGP0325-10ug, ATGP0325-20ug, ATGP0325-50ug, ATGP0325-100ug, ATGP0325-250ug, ATGP0325-500ug, ATGP0325-1mg, ATGP0325-10, ATGP0325-20, ATGP0325-50, ATGP0325-100, ATGP0325-250, ATGP0325-500, ATGP0325-1
Available
Manufacturer - Type	Recombinant Protein
Manufacturer - Applications	SDS-PAGE, Enzyme Activity
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	29.2 kDa (260aa) confirmed by MALDI-TOF
Description	Carbonic anhydrase 2 (CA2) is one of fourteen forms of human alpha carbonic anhydrases. Carbonic anhydrase catalyzes reversible hydration of carbon dioxide. CA2 is a cytosolic enzyme with the highest activity among all known CAs. Mutations in the CA2 gene result in the CA2 deficiency syndrome, an autosomal recessive disorder that produces osteopetrosis, renal tubular acidosis and cerebral calcification. Recombinant human CA2 was expressed in E. coli and purified by using conventional chromatography.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species	Human
Gene Category	Enzymes & Proteases
Domain	1-260aa
Bioactivity Comment Only	Specific activity is > 7, 000pmol/min/ug, and is defined as the amount of enzyme that hydrolyze 1.0pmole of 4-nitrophenyl acetate to 4-nitrophenol per minute at pH 8.0 at 37C.
Species of Protein	Human
Manufacturer - Search Terms	Carbonic Anhydrase II, CA2, Carbonic anhydrase 2, CA-II, CAC, CA 2, CA II, CA2, CAI, Car 2, Car2, Carbonate dehydratase II, Carbonic anhydrase B, Carbonic anhydrase C, Carbonic anhydrase II, Carbonic dehydratase., ATGP0325-10ug, ATGP0325-20ug, ATGP0325-50ug, ATGP0325-100ug, ATGP0325-250ug, ATGP0325-500ug, ATGP0325-1mg, ATGP0325-10, ATGP0325-20, ATGP0325-50, ATGP0325-100, ATGP0325-250, ATGP0325-500, ATGP0325-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 ug

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Delivery expected until 7/31/2025

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