Comparison

Recombinant human IL-6 protein

Item no. NKM-ATGP0352-500ug
Manufacturer NKMAX
Amount 500 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH M>VPPGEDSKD VAAPHRQPLT SSERIDKQIR YILDGISALR KETCNKSNMC ESSKEALAEN NLNLPKMAEK DGCFQSGFNE ETCLVKIITG LLEFEVYLEY LQNRFESSEE QARAVQMSTK VLIQFLQKKA KNLDAITTPD PTTNASLLTK LQAQNQWLQD MTTHLILRSF KEFLQSSLRA LRQM
Citations Ishihara, et al. (2002) Cytokine Growth Factor Rev. 13(4-5):357-68.
Vgontzas AN, et al. (2005) Neuroimmunomodulation.12, 131-40.
NCBI NP_000591.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Interleukin-6,B-cell stimulatory factor 2,BSF-2,CTL differentiation factor,CDF,Hybridoma growth factor,Interferon beta-2,IFN-beta-2,IFNB2,HGF,HSF
Similar products IL-6, HGF, IL6, IFNB2, Interleukin-6, FNRB, MDF2, MSK12, Fibronectin receptor subunit beta, CD29, Interleukin 6, IL 6, GPIIA, Integrin beta 1, BSF2, HSF, VLAB, Integrin beta1, BSF 2, Interferon beta 2, Interleukin6, VLA-4 subunit bet, VLA4 subunit bet, VLA 4 subunit bet, MSK 12, IFNB 2, IFN B2, IFN B 2, I L6, GP IIA, Glycoprotein Iia, ATGP0352-10ug, ATGP0352-20ug, ATGP0352-50ug, ATGP0352-100ug, ATGP0352-250ug, ATGP0352-500ug, ATGP0352-1mg, ATGP0352-010, ATGP0352-020, ATGP0352-050, ATGP0352-100, ATGP0352-250, ATGP0352-500, ATGP0352-01M
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Bioactivity
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
23.1 kDa (204aa) confirmed by MALDI-TOF
Description
Interleukin-6, as known as IL-6, is an immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. It is also a 'myokine, ' a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 acts as both a pro-inflammatory and anti-inflammatory cytokine. Smooth muscle cells in the tunica media of many blood vessels also produce IL-6. It is mediated through its inhibitory effects on TNF-alpha and IL-1, and activation of IL-1ra and IL-10. Recombinant interleukin-6 was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Hormones & Cytokines
Domain
30-212aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured in a cell proliferation assay using TF-1 human erythroleukemic cell. The ED50 range ≤ 0.8ng/ml.
Species of Protein
Human
Manufacturer - Search Terms
VLAB, VLA-4 subunit bet, VLA4 subunit bet, VLA 4 subunit bet, MSK12, MSK 12, MDF2, Interleukin-6, Interleukin6, Interleukin 6, Interferon beta 2, Integrin beta1, Integrin beta 1, IL-6, IL6, IL 6, IFNB2, IFNB 2, IFN B2, IFN B 2, I L6, HSF, HGF, GPIIA, GP IIA, Glycoprotein Iia, FNRB, Fibronectin receptor subunit beta, CD29, BSF2, BSF 2, ATGP0352-10ug, ATGP0352-20ug, ATGP0352-50ug, ATGP0352-100ug, ATGP0352-250ug, ATGP0352-500ug, ATGP0352-1mg, ATGP0352-010, ATGP0352-020, ATGP0352-050, ATGP0352-100, ATGP0352-250, ATGP0352-500, ATGP0352-01M

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 ug
Available: In stock
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