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Recombinant human Otubain-1/OTUB1 protein

Recombinant human Otubain-1/OTUB1 protein

Item no.	NKM-ATGP0354-20ug
Manufacturer	NKMAX
Amount	20 ug
Quantity options	100 ug 20 ug 500 ug
Category	Neuroscience Targets for Rodent Neurosciences Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Autophagy SDS-PAGE
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 95% by SDS-PAGE
Sequence	<MGSSHHHHHH SSGLVPRGSH> MAAEEPQQQK QEPLGSDSEG VNCLAYDEAI MAQQDRIQQE IAVQNPLVSE RLELSVLYKE YAEDDNIYQQ KIKDLHKKYS YIRKTRPDGN CFYRAFGFSH LEALLDDSKE LQRFKAVSAK SKEDLVSQGF TEFTIEDFHN TFMDLIEQVE KQTSVADLLA SFNDQSTSDY LVVYLRLLTS GYLQRESKFF EHFIEGGRTV KEFCQQEVEP
Citations	Balakirev MY., et al. (2003) EMBO Rep. 4(5):517-22. Soares L., et al. (2004) Nat Immunol. 5(1):45-54.
NCBI	NP_060140
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	ubiquitin thioesterase Otubain 1,OTB1,OTu1,ubiquitin thioesterase Otubain 1 Deubiquitinating enzyme OTuB1,OTu domain containing ubiquitin aldehyde binding protein 1,Otubain 1,ubiquitin specific processing protease OTuB1,ubiquitin thioesterase OTuB1
Similar products	OTB1, Otubain 1, Otubain1, ubiquitin thioesterase Otubain 1, OTu1, ubiquitin thioesterase Otubain 1 Deubiquitinating enzyme OTuB1, OTu domain containing ubiquitin aldehyde binding protein 1, ubiquitin specific processing protease OTuB1, ubiquitin thioesterase OTuB1., ATGP0354-10ug, ATGP0354-20ug, ATGP0354-50ug, ATGP0354-100ug, ATGP0354-250ug, ATGP0354-500ug, ATGP0354-1mg, ATGP0354-10, ATGP0354-20, ATGP0354-50, ATGP0354-100, ATGP0354-250, ATGP0354-500, ATGP0354-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	33.4 kDa (291aa) confirmed by MALDI-TOF
Description	Otubain 1, also known as OTuB1, is a member of the OuT (ovarian tumor) superfamily of predicted cysteine proteases and inhibits cytokine gene transcription in the immune system via its interaction with a ubiquitin protease and E3 ubiquitin ligase. This protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function of polyubiquitin chain growth. Recombinant OTuB1 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Antigen Species	Human
Gene Category	Enzymes & Proteases
Domain	1-271aa
Species of Protein	Human
Manufacturer - Search Terms	Otubain1, ubiquitin thioesterase Otubain 1, OTB1, OTu1, ubiquitin thioesterase Otubain 1 Deubiquitinating enzyme OTuB1, OTu domain containing ubiquitin aldehyde binding protein 1, Otubain 1, ubiquitin specific processing protease OTuB1, ubiquitin thioesterase OTuB1., ATGP0354-10ug, ATGP0354-20ug, ATGP0354-50ug, ATGP0354-100ug, ATGP0354-250ug, ATGP0354-500ug, ATGP0354-1mg, ATGP0354-10, ATGP0354-20, ATGP0354-50, ATGP0354-100, ATGP0354-250, ATGP0354-500, ATGP0354-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 ug

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Delivery expected until 7/31/2025

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