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Recombinant human DFF45/ICAD protein

Recombinant human DFF45/ICAD protein

Item no.	NKM-ATGP0368-20ug
Manufacturer	NKMAX
Amount	20 ug
Quantity options	100 ug 20 ug 500 ug
Category	Oncology By Cell Type Peptides & Proteins Recombinant Proteins SDS-PAGE
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 90% by SDS-PAGE
Sequence	<MGSSHHHHHH SSGLVPRGSH> MEVTGDAGVP ESGEIRTLKP CLLRRNYSRE QHGVAASCLE DLRSKACDIL AIDKSLTPVT LVLAEDGTIV DDDDYFLCLP SNTKFVALAS NEKWAYNNSD GGTAWISQES FDVDETDSGA GLKWKNVARQ LKEDLSSIIL LSEEDLQMLV DAPCSDLAQE LRQSCATVQR LQHTLQQVLD QREEVRQSKQ LLQLYLQALE KEGSLLSKQE
Citations	McCarty JS., et al. (1999) Biochem Biophys Res Commun. 264(1):176-80. Gu J., et al. (1999) J Biol Chem. 274(30):20759-62.
NCBI	AAH07721.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	DNA fragmentation factor subunit alpha.,FF-45,DFF1,ICAD,DNA fragmentation factor subunit alpha,A330085O09Rik,ICAD L,ICAD S,DFF 1,Caspase activated deoxyribonuclease inhibitor short form,DFF 45,DFF alpha,DFF35,DFF45,DFFA,Caspase-activated deoxyribonuclease inhibitor short form,Dffa DNA fragmentation factor,alpha subunit,DNA fragmentation factor 45 kDa subunit,DNA Fragmentation Factor Alpha Subunit,DNA fragmentation factor subunit alpha,DNA fragmentation factor,45 kD,alpha subunit,DNA fragmentation factor,45kDa,alpha polypeptide,DNA fragmentation factor,45kDa,alpha polypeptide (DFFA),transcript variant 1,RP23 121D17.3,DNA fragmentation factor,alpha subunit,DNAation factor 45 kDa subunit,H13,Inhibitor of CAD,Inhibitor of Caspase Activated DNase,MGC143066,OTTHuMP00000001903,OTTHuMP00000001904,
Similar products	ICAD, DFF45, DFFA, H13, alpha subunit, alpha polypeptide, DFF1, DNA fragmentation factor, 45kDa, ICAD L, ICAD S, Caspase activated deoxyribonuclease inhibitor short form, DFF 1, DFF 45, DFF alpha, DFF35, Dffa DNA fragmentation factor, DNA fragmentation factor 45 kDa subunit, DNA Fragmentation Factor Alpha Subunit, DNA fragmentation factor subunit alpha, 45 kD, transcript variant 1, A330085O09Rik, Inhibitor of CAD, Inhibitor of Caspase Activated DNase, MGC143066, RP23 121D17.3, alpha polypeptide (DFFA), DNAation factor 45 kDa subunit, DNA fragmentation factor subunit alpha., FF-45, Caspase-activated deoxyribonuclease inhibitor short form, OTTHuMP00000001903, OTTHuMP00000001904, ATGP0368-10ug, ATGP0368-20ug, ATGP0368-50ug, ATGP0368-100ug, ATGP0368-250ug, ATGP0368-500ug, ATGP0368-1mg, ATGP0368-10, ATGP0368-20, ATGP0368-50
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	38.7 kDa (351aa) confirmed by MALDI-TOF
Description	DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA, also known as DNA fragmentation factor subunit alpha, is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Recombinant DFFA protein was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 1mM DTT
Antigen Species	Human
Gene Category	Apoptosis
Domain	1-331aa
Species of Protein	Human
Manufacturer - Search Terms	DFF45, ICAD, DNA fragmentation factor subunit alpha., FF-45, DFF1, ICAD, DNA fragmentation factor subunit alpha, A330085O09Rik, ICAD L, ICAD S, DFF 1, Caspase activated deoxyribonuclease inhibitor short form, DFF 45, DFF alpha, DFF35, DFF45, DFFA, Caspase-activated deoxyribonuclease inhibitor short form, Dffa DNA fragmentation factor, alpha subunit, DNA fragmentation factor 45 kDa subunit, DNA Fragmentation Factor Alpha Subunit, DNA fragmentation factor subunit alpha, DNA fragmentation factor, 45 kD, alpha subunit, DNA fragmentation factor, 45kDa, alpha polypeptide, DNA fragmentation factor, 45kDa, alpha polypeptide (DFFA), transcript variant 1, RP23 121D17.3, DNA fragmentation factor, alpha subunit, DNAation factor 45 kDa subunit, H13, Inhibitor of CAD, Inhibitor of Caspase Activated DNase, MGC143066, OTTHuMP00000001903, OTTHuMP00000001904, ATGP0368-10ug, ATGP0368-20ug, ATGP0368-50ug, ATGP0368-100ug, ATGP0368-250ug, ATGP0368-500ug, ATGP0368-1mg, ATGP0368-10, ATGP0368-20, ATGP0368-50, ATGP0368-10
Manufacturer - Alternative Names	DNA fragmentation factor subunit alpha., FF-45, DFF1, ICAD, DNA fragmentation factor subunit alpha, A330085O09Rik, ICAD L, ICAD S, DFF 1, Caspase activated deoxyribonuclease inhibitor short form, DFF 45, DFF alpha, DFF35, DFF45, DFFA, Caspase-activated deoxyribonuclease inhibitor short form, Dffa DNA fragmentation factor, alpha subunit, DNA fragmentation factor 45 kDa subunit, DNA Fragmentation Factor Alpha Subunit, DNA fragmentation factor subunit alpha, DNA fragmentation factor, 45 kD, alpha subunit, DNA fragmentation factor, 45kDa, alpha polypeptide, DNA fragmentation factor, 45kDa, alpha polypeptide (DFFA), transcript variant 1, RP23 121D17.3, DNA fragmentation factor, alpha subunit, DNAation factor 45 kDa subunit, H13, Inhibitor of CAD, Inhibitor of Caspase Activated DNase, MGC143066, OTTHuMP00000001903, OTTHuMP00000001904

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 ug

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Delivery expected until 7/31/2025

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