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Recombinant human Smad3 protein

Recombinant human Smad3 protein

Item no.	NKM-ATGP0421-500ug
Manufacturer	NKMAX
Amount	500 ug
Quantity options	100 ug 20 ug 500 ug
Category	Oncology Peptides & Proteins Recombinant Proteins SDS-PAGE By Organ Colorectal Cancer
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 90% by SDS-PAGE
Sequence	<MGSSHHHHHH SSGLVPRGSH> MSSILPFTPP IVKRLLGWKK GEQNGQEEKW CEKAVKSLVK KLKKTGQLDE LEKAITTQNV NTKCITIPRS LDGRLQVSHR KGLPHVIYCR LWRWPDLHSH HELRAMELCE FAFNMKKDEV CVNPYHYQRV ETPVLPPVLV PRHTEIPAEF PPLDDYSHSI PENTNFPAGI EPQSNIPETP PPGYLSEDGE TSDHQMNHSM DAGSPNLSPN
Citations	Zhang Y., et al. (1996) Nature. 383(6596):168-72. Wang H., et al. (2005) J Biol Chem. 280(7):5154-62.
NCBI	NP_005893
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Mothers against decapentaplegic homolog 3,HSPC193,HsT17436,JV15-2,MADH3,Mothers against decapentaplegic homolog 3 DKFZP586N0721,DKFZp686J10186,hMAD 3,hSMAD3,MAD (mothers against decapentaplegic Drosophila) homolog 3,HST17436,JV15 2,JV152,MAD3,MADH 3,MGC60396,Mothers against DPP homolog 3,SMA and MAD related protein 3,SMAD,SMAD 3,SMAD3,
Similar products	Smad3, ATGP0421-10ug, ATGP0421-20ug, ATGP0421-50ug, ATGP0421-100ug, ATGP0421-250ug, ATGP0421-500ug, ATGP0421-1mg, ATGP0421-10, ATGP0421-20, ATGP0421-50, ATGP0421-100, ATGP0421-250, ATGP0421-500, ATGP0421-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	50.2 kDa (445aa) confirmed by MALDI-TOF
Description	SMAD3, also known as mothers against decapentaplegic homolog 3, belongs to the SMAD family of proteins that mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. Small moleucule inhibitors of Smad3 may have tremendous clinical potential in the treatment of pathological fibrotic diseases. Recombinant SMAD3 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration	0.5mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl and 1mM DTT
Antigen Species	Human
Gene Category	Epigenomics (Transcription & Translation)
Domain	1-425aa
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Species of Protein	Human
Manufacturer - Search Terms	Smad3, ATGP0421-10ug, ATGP0421-20ug, ATGP0421-50ug, ATGP0421-100ug, ATGP0421-250ug, ATGP0421-500ug, ATGP0421-1mg, ATGP0421-10, ATGP0421-20, ATGP0421-50, ATGP0421-100, ATGP0421-250, ATGP0421-500, ATGP0421-1
Manufacturer - Alternative Names	Mothers against decapentaplegic homolog 3, HSPC193, HsT17436, JV15-2, MADH3, Mothers against decapentaplegic homolog 3 DKFZP586N0721, DKFZp686J10186, hMAD 3, hSMAD3, MAD (mothers against decapentaplegic Drosophila) homolog 3, HST17436, JV15 2, JV152, MAD3, MADH 3, MGC60396, Mothers against DPP homolog 3, SMA and MAD related protein 3, SMAD, SMAD 3, SMAD3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 7/31/2025

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