Comparison

Recombinant human Frataxin protein

Item no. NKM-ATGP0448-20ug
Manufacturer NKMAX
Amount 20 ug
Quantity options 100 ug 20 ug 500 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 95% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH M>LRTDIDATC TPRRASSNQR GLNQIWNVKK QSVYLMNLRK SGTLGHPGSL DETTYERLAE ETLDSLAEFF EDLADKPYTF EDYDVSFGSG VLTVKLGGDL GTYVINKQTP NKQIWLSSPS SGPKRYDWTG KNWVYSHDGV SLHELLAAEL TKALKTKLDL SSLAYSGKDA
Citations Campuzano V., et al. (1996) Science. 271(5254):1423-7.
Shan Y., et al. (2007) Hum Mol Genet. 16(8):929-41.
NCBI NP_000135.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CyaY,FA,FARR,FRDA,X25,FXN,Friedreich ataxia protein.
Similar products Frataxin, ATGP0448-10ug, ATGP0448-20ug, ATGP0448-50ug, ATGP0448-100ug, ATGP0448-250ug, ATGP0448-500ug, ATGP0448-1mg, ATGP0448-10, ATGP0448-20, ATGP0448-50, ATGP0448-100, ATGP0448-250, ATGP0448-500, ATGP0448-1
Available
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
21.1 kDa (190aa) confirmed by MALDI-TOF
Description
Frataxin, also known as FXN, is an iron binding protein which belongs to FRATAXIN family. It is an anti-apoptotic protein which prevents mitochondrial damage, reactive oxygen species production and act as either an iron chaperone or an iron storage protein. Frataxin is localized to the mitochondrion and regulating mitochondrial iron transport and respiration. Defects in this protein cause Friedreich ataxia. Recombinant Frataxin protein was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.5) containing 20% glycerol, 0.1M NaCl 1mM DTT
Antigen Species
Human
Gene Category
Apoptosis
Domain
42-210aa
Species of Protein
Human
Manufacturer - Search Terms
Frataxin, ATGP0448-10ug, ATGP0448-20ug, ATGP0448-50ug, ATGP0448-100ug, ATGP0448-250ug, ATGP0448-500ug, ATGP0448-1mg, ATGP0448-10, ATGP0448-20, ATGP0448-50, ATGP0448-100, ATGP0448-250, ATGP0448-500, ATGP0448-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 20 ug
Available: In stock
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