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Recombinant human Frataxin protein

Recombinant human Frataxin protein

Item no.	NKM-ATGP0448-20ug
Manufacturer	NKMAX
Amount	20 ug
Quantity options	100 ug 20 ug 500 ug
Category	Neuroscience Aging & Neurological Disorders Neural Signaling Peptides & Proteins Recombinant Proteins SDS-PAGE
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 95% by SDS-PAGE
Sequence	<MGSSHHHHHH SSGLVPRGSH M>LRTDIDATC TPRRASSNQR GLNQIWNVKK QSVYLMNLRK SGTLGHPGSL DETTYERLAE ETLDSLAEFF EDLADKPYTF EDYDVSFGSG VLTVKLGGDL GTYVINKQTP NKQIWLSSPS SGPKRYDWTG KNWVYSHDGV SLHELLAAEL TKALKTKLDL SSLAYSGKDA
Citations	Campuzano V., et al. (1996) Science. 271(5254):1423-7. Shan Y., et al. (2007) Hum Mol Genet. 16(8):929-41.
NCBI	NP_000135.2
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CyaY,FA,FARR,FRDA,X25,FXN,Friedreich ataxia protein.
Similar products	Frataxin, ATGP0448-10ug, ATGP0448-20ug, ATGP0448-50ug, ATGP0448-100ug, ATGP0448-250ug, ATGP0448-500ug, ATGP0448-1mg, ATGP0448-10, ATGP0448-20, ATGP0448-50, ATGP0448-100, ATGP0448-250, ATGP0448-500, ATGP0448-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	21.1 kDa (190aa) confirmed by MALDI-TOF
Description	Frataxin, also known as FXN, is an iron binding protein which belongs to FRATAXIN family. It is an anti-apoptotic protein which prevents mitochondrial damage, reactive oxygen species production and act as either an iron chaperone or an iron storage protein. Frataxin is localized to the mitochondrion and regulating mitochondrial iron transport and respiration. Defects in this protein cause Friedreich ataxia. Recombinant Frataxin protein was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.5) containing 20% glycerol, 0.1M NaCl 1mM DTT
Antigen Species	Human
Gene Category	Apoptosis
Domain	42-210aa
Species of Protein	Human
Manufacturer - Search Terms	Frataxin, ATGP0448-10ug, ATGP0448-20ug, ATGP0448-50ug, ATGP0448-100ug, ATGP0448-250ug, ATGP0448-500ug, ATGP0448-1mg, ATGP0448-10, ATGP0448-20, ATGP0448-50, ATGP0448-100, ATGP0448-250, ATGP0448-500, ATGP0448-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 ug

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Delivery expected until 7/31/2025

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