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Recombinant human HEXIM1 protein

Recombinant human HEXIM1 protein

Item no.	NKM-ATGP0475-500ug
Manufacturer	NKMAX
Amount	500 ug
Quantity options	100 ug 20 ug 500 ug
Category	Neuroscience Molecular Targets for Neuroscience Peptides & Proteins Recombinant Proteins SDS-PAGE
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 90% by SDS-PAGE
Sequence	<MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSH>MAE PFLSEYQHQP QTSNCTGAAA VQEELNPERP PGAEERVPEE DSRWQSRAFP QLGGRPGPEG EGSLESQPPP LQTQACPESS CLREGEKGQN GDDSSAGGDF PPPAEVEPTP EAELLAQPCH DSEASKLGAP AAGGEEEWGQ QQRQLGKKKH RRRPSKKKRH WKPYYKLTWE EKKKFDEKQS LRASRIRAEM
Citations	Shimizu N., et al. (2005) Proc. Natl. Acad. Sci. u.S.A. 102(24):8555-60 Li Q., et al. (2007) Nucleic Acids Res 35(8):2503-12.
NCBI	NP_006451.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Hexamethylene bis-acetamide inducible 1,CLP1,EDG1,HIS1,MAQ1,Hexamethylene bis-acetamide inducible 1 Cardiac lineage protein 1,CLP 1,EDG 1,FLJ13562,Hexamethylene bis acetamide inducible 1,Hexamethylene bis acetamide inducible protein,Hexamethylene bis acetamide inducible transcript 1,HEXIM 1,HEXIM1 protein,HIS 1,HMBA inducible,MAQ 1,Menage a quatre 1.
Similar products	HEXIM1, CLP1, EDG1, HIS1, MAQ1, FLJ13562, CLP 1, EDG 1, Hexamethylene bis acetamide inducible 1, Hexamethylene bis acetamide inducible protein, Hexamethylene bis acetamide inducible transcript 1, HEXIM 1, HEXIM1 protein, HIS 1, HMBA inducible, MAQ 1, Hexamethylene bis-acetamide inducible 1, Hexamethylene bis-acetamide inducible 1 Cardiac lineage protein 1, Menage a quatre 1., ATGP0475-10ug, ATGP0475-20ug, ATGP0475-50ug, ATGP0475-100ug, ATGP0475-250ug, ATGP0475-500ug, ATGP0475-1mg, ATGP0475-10, ATGP0475-20, ATGP0475-50, ATGP0475-100, ATGP0475-250, ATGP0475-500, ATGP0475-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	44.8 kDa (396aa) confirmed by MALDI-TOF
Description	HEXIM1 is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. This protein has been shown to form a protein-RNA complex composed of 7SK small nuclear RNA and positive transcription elongation factor b (P-TEFb), which is composed of cyclin-dependent kinase 9 (CDK9) and cyclin T1, and to inhibit the kinase activity of CDK9, thereby suppressing RNA polymerase II-dependent transcriptional elongation. Recombinant HEXIM1 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration	0.5mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl
Antigen Species	Human
Gene Category	Epigenomics (Transcription & Translation)
Domain	1-359aa
Species of Protein	Human
Manufacturer - Search Terms	HEXIM1, Hexamethylene bis-acetamide inducible 1, CLP1, EDG1, HIS1, MAQ1, Hexamethylene bis-acetamide inducible 1 Cardiac lineage protein 1, CLP 1, EDG 1, FLJ13562, Hexamethylene bis acetamide inducible 1, Hexamethylene bis acetamide inducible protein, Hexamethylene bis acetamide inducible transcript 1, HEXIM 1, HEXIM1 protein, HIS 1, HMBA inducible, MAQ 1, Menage a quatre 1., ATGP0475-10ug, ATGP0475-20ug, ATGP0475-50ug, ATGP0475-100ug, ATGP0475-250ug, ATGP0475-500ug, ATGP0475-1mg, ATGP0475-10, ATGP0475-20, ATGP0475-50, ATGP0475-100, ATGP0475-250, ATGP0475-500, ATGP0475-1
Manufacturer - Alternative Names	Hexamethylene bis-acetamide inducible 1, CLP1, EDG1, HIS1, MAQ1, Hexamethylene bis-acetamide inducible 1 Cardiac lineage protein 1, CLP 1, EDG 1, FLJ13562, Hexamethylene bis acetamide inducible 1, Hexamethylene bis acetamide inducible protein, Hexamethylene bis acetamide inducible transcript 1, HEXIM 1, HEXIM1 protein, HIS 1, HMBA inducible, MAQ 1, Menage a quatre 1.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 7/31/2025

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