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Recombinant human PDCD6IP protein

Recombinant human PDCD6IP protein

Item no.	NKM-ATGP0482-500ug
Manufacturer	NKMAX
Amount	500 ug
Quantity options	100 ug 20 ug 500 ug
Category	Peptides & Proteins Recombinant Proteins SDS-PAGE
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 95% by SDS-PAGE
Sequence	<MGSSHHHHHH SSGLVPRGSH> MATFISVQLK KTSEVDLAKP LVKFIQQTYP SGGEEQAQYC RAAEELSKLR RAAVGRPLDK HEGALETLLR YYDQICSIEP KFPFSENQIC LTFTWKDAFD KGSLFGGSVK LALASLGYEK SCVLFNCAAL ASQIAAEQNL DNDEGLKIAA KHYQFASGAF LHIKETVLSA LSREPTVDIS PDTVGTLSLI MLAQAQEVFF LKATRDKMKD
Citations	Morita E., et al. (2007) EMBO J. 26(19):4215-27. Katoh K., et al. (2004) Arch Biochem Biophys. 421(1):159-65.
NCBI	NP_037506.2
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Programmed cell death 6 interacting protein,PDCD6-interacting protein,ALG-2 interacting protein X,ALG-2-interacting protein 1,Alix,AIP1,Hp95
Similar products	Alix, ATGP0482-10ug, ATGP0482-20ug, ATGP0482-50ug, ATGP0482-100ug, ATGP0482-250ug, ATGP0482-500ug, ATGP0482-1mg, ATGP0482-10, ATGP0482-20, ATGP0482-50, ATGP0482-100, ATGP0482-250, ATGP0482-500, ATGP0482-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	45.8 kDa (412aa) confirmed by MALDI-TOF
Description	Alix, also known as PDCD6IP, is a cytoplasmic protein that interacts with apoptosis-associated proteins (ALG-2 and PDCD6) and with the endocytosis-regulator CIN85. It's involved in concentration and sorting of cargo proteins of the multivesicular body for incorporation into intralumenal vesicles that are generated by invagination and scission from the limiting membrane of the endosome. Overexpression of this protein and endophilins results in cytoplasmic vacuolization which may be partly responsible for the protection against cell death. Recombinant PDCD6IP protein was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 1mM DTT
Antigen Species	Human
Gene Category	Apoptosis
Domain	1-392aa
Species of Protein	Human
Manufacturer - Search Terms	Alix, ATGP0482-10ug, ATGP0482-20ug, ATGP0482-50ug, ATGP0482-100ug, ATGP0482-250ug, ATGP0482-500ug, ATGP0482-1mg, ATGP0482-10, ATGP0482-20, ATGP0482-50, ATGP0482-100, ATGP0482-250, ATGP0482-500, ATGP0482-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 7/31/2025

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