Comparison

Recombinant human 6-Phosphogluconate Dehydrogenase/PGD protein

Item no. NKM-ATGP0504-500ug
Manufacturer NKMAX
Amount 500 ug
Quantity options 100 ug 20 ug 500 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 95% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MAQADIALIG LAVMGQNLIL NMNDHGFVVC AFNRTVSKVD DFLANEAKGT KVVGAQSLKE MVSKLKKPRR IILLVKAGQA VDDFIEKLVP LLDTGDIIID GGNSEYRDTT RRCRDLKAKG ILFVGSGVSG GEEGARYGPS LMPGGNKEAW PHIKTIFQGI AAKVGTGEPC CDWVGDEGAG HFVKMVHNGI EYGDMQLICE AYHLMKDVLG MA
Citations Le TD., et al. (2010) Proc Natl Acad Sci u S A. 107(7):3198-203.
Tagen M., et al. (2009) J Immunol. 183(10):6313-9.
NCBI NP_002622
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias 6-phosphogluconate dehydrogenase,Decarboxylating,PGDH,Phosphogluconate dehydrogenase,6PGD
Similar products PGD, decarboxylating, 6PGD, Phosphogluconate dehydrogenase, 6 phosphogluconate dehydrogenase, C78335, RP23-249G3.4, Phosphogluconate dehydrogenase 0610042A05Rik, Au019875, OTTMuSP00000011754, 6-Phosphogluconate Dehydrogenase, ATGP0504-10ug, ATGP0504-20ug, ATGP0504-50ug, ATGP0504-100ug, ATGP0504-250ug, ATGP0504-500ug, ATGP0504-1mg, ATGP0504-10, ATGP0504-20, ATGP0504-50, ATGP0504-100, ATGP0504-250, ATGP0504-500, ATGP0504-1
Available
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
55.3 kDa (503aa)
Description
PGD (Phosphogluconate dehydrogenas), also known as 6PGD, is a 483 amino acid enzyme that is involved in the pentose phosphate shunt. Pentose is required for nucleic acid biosynthesis and the pentose phosphate cycle is a major source of NADPH. PGD deficiency increases the level of erythrocyte pyruvate kinase (PK) activity and reduces glutathione synthetase (GSH), resulting in hemolysis. Defects in PGD are generally asymptomatic and are inherited in an autosomal dominant fashion. Recombinant human PGD protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 0.1M Nacl, 10% glycerol
Antigen Species
Human
Gene Category
Redox Proteins
Domain
1-483aa
Species of Protein
Human
Manufacturer - Search Terms
6-Phosphogluconate Dehydrogenase, PGD, Phosphogluconate dehydrogenase, 6PGD, Phosphogluconate dehydrogenase 0610042A05Rik, Au019875, C78335, 6 phosphogluconate dehydrogenase, decarboxylating, OTTMuSP00000011754, RP23-249G3.4, ATGP0504-10ug, ATGP0504-20ug, ATGP0504-50ug, ATGP0504-100ug, ATGP0504-250ug, ATGP0504-500ug, ATGP0504-1mg, ATGP0504-10, ATGP0504-20, ATGP0504-50, ATGP0504-100, ATGP0504-250, ATGP0504-500, ATGP0504-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 ug
Available: In stock
available

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