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Recombinant human LTA/TNF-beta protein

Recombinant human LTA/TNF-beta protein

Item no.	NKM-ATGP0517-10ug
Manufacturer	NKMAX
Amount	10 ug
Quantity options	10 ug 250 ug 50 ug
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes By Cell Type Carcinoma Hematology Myeloma Peptides & Proteins Recombinant Proteins Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis SDS-PAGE Cardiovascular Research Hypertension
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 90% by SDS-PAGE
Sequence	MGSSHHHHHH SSGLVPRGSH MLPGVGLTPS AAQTARQHPK MHLAHSTLKP AAHLIGDPSK QNSLLWRANT DRAFLQDGFS LSNNSLLVPT SGIYFVYSQV VFSGKAYSPK ATSSPLYLAH EVQLFSSQYP FHVPLLSSQK MVYPGLQEPW LHSMYHGAAF QLTQGDQLST HTDGIPHLVL SPSTVFFGAF AL
Citations	Messer G, et al. (1991) J Exp Med. 173(1):209-19 Banner DW, et al. (1993) Cell. 73(3):431-45.
NCBI	NP_001153212
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Lymphotoxin-alpha,LT-alpha,TNF-beta,Tumor necrosis factor ligand superfamily member 1,TNFB,TNFSF1,TNF superfamily,member 1
Similar products	LTA, TNF B, TNF b, Tumor necrosis factor ligand superfamily member 1, TNFB, TNFSF1, TNFbeta, LT, DIF, Differentiation inducing factor, Hemorrhagic factor, LT alpha, LTalpha, Lymphotoxin alpha, Lymphotoxin alpha (TNF superfamily, member 1), Natural killer cytotoxic factor, Necrosin, NKCF, TNF superfamily member 1, TNFSF 1, Tumor necrosis factor beta, Tumor necrosis factor superfamily member 1, Coley's toxin, Lymphotoxin a1, CLTalpha, OTTHuMP00000037612, OTTHuMP00000037613, ATGP0517-10ug, ATGP0517-20ug, ATGP0517-50ug, ATGP0517-100ug, ATGP0517-250ug, ATGP0517-500ug, ATGP0517-1mg, ATGP0517-10, ATGP0517-20, ATGP0517-50, ATGP0517-100, ATGP0517-250, ATGP0517-500, ATGP0517-1
Available
Manufacturer - Type	Recombinant Protein
Manufacturer - Applications	SDS-PAGE, Bioactivity
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	20.9 kDa (192aa) confirmed by MALDI-TOF
Description	TNF beta, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Recombinant TNF beta protein was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration	0.25mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 30% glycerol, 0.1M NaCl, 1mM DTT
Antigen Species	Human
Gene Category	Hormones & Cytokines
Domain	35-205aa
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only	Measured in a cytotoxicity assay using L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 range ≤ 1ng/ml.
Species of Protein	Human
Manufacturer - Search Terms	Lymphotoxin a1, TNF b, Lymphotoxin alpha, CLTalpha, Coley's toxin, DIF, Differentiation inducing factor, Hemorrhagic factor, LT, LT alpha, LTA, LTalpha, Lymphotoxin alpha, Lymphotoxin alpha (TNF superfamily, member 1), Natural killer cytotoxic factor, Necrosin, NKCF, OTTHuMP00000037612, OTTHuMP00000037613, TNF B, TNF superfamily member 1, TNFB, TNFbeta, TNFSF 1, TNFSF1, Tumor necrosis factor beta, Tumor necrosis factor ligand superfamily member 1, Tumor necrosis factor superfamily member 1, Lymphotoxin alpha, ATGP0517-10ug, ATGP0517-20ug, ATGP0517-50ug, ATGP0517-100ug, ATGP0517-250ug, ATGP0517-500ug, ATGP0517-1mg, ATGP0517-10, ATGP0517-20, ATGP0517-50, ATGP0517-100, ATGP0517-250, ATGP0517-500, ATGP0517-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 7/31/2025

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