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Recombinant human 17 beta-HSD10/HSD17B10 protein

Recombinant human 17 beta-HSD10/HSD17B10 protein

Item no.	NKM-ATGP0518-20ug
Manufacturer	NKMAX
Amount	20 ug
Quantity options	100 ug 20 ug 500 ug
Category	Oncology Neuroscience Metabolism Diabetes Neural Mitochondrial Function By Cell Type Carcinoma Sarcoma Peptides & Proteins Recombinant Proteins SDS-PAGE
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 95% by SDS-PAGE
Sequence	<MGSSHHHHHH SSGLVPRGSH> MVAVITGGAS GLGLATAERL VGQGASAVLL DLPNSGGEAQ AKKLGNNCVF APADVTSEKD VQTALALAKG KFGRVDVAVN CAGIAVASKT YNLKKGQTHT LEDFQRVLDV NLMGTFNVIR LVAGEMGQNE PDQGGQRGVI INTASVAAFE GQVGQAAYSA SKGGIVGMTL PIARDLAPIG IRVMTIAPGL FGTPLLTSLP EKVCNFLASQ
Citations	Hoizmann J., et al. (2008) Cell. 135(3):462-74. Yan SD., et al. (1997) Nature. 389(6652):689-95.
NCBI	NP_004484.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Hydroxysteroid 17-beta dehydrogenase 10,HADH2,MRXS10,ERAB,SCHAD,MHBD,17b-HSD10,ABAD,SDR5C1,MRPP2,CAMR,Hydroxyacyl-Coenzyme A dehydrogenase,type II,mental retardation,X-linked,syndromic 10,Hydroxysteroid (17-beta) dehydrogenase 10,type 10 17b-HSD,type 10 17beta-hydroxysteroid dehydrogenase,AB-binding alcohol dehydrogenase,short chain dehydrogenase/reductase family 5C,member 1,mitochondrial RNase P subunit 2
Similar products	ERAB, HSD17B10, SCHAD, ABAD, CAMR, HADH2, HCD2, MHBD, MRPP2, MRX17, SDR5C1, Mitochondrial L3 Hydroxyacyl CoA Dehydrogenase, 17 beta hydroxysteroid dehydrogenase 10, 17 beta hydroxysteroid dehydrogenase type 10, 17b HSD10, 3 hydroxy 2 methylbutyryl CoA dehydrogenase, 3 hydroxyacyl CoA dehydrogenase type 2, 3-hydroxyacyl-CoA dehydrogenase type-2, Mitochondrial ribonuclease P protein 2, 3 hydroxyacyl CoA dehydrogenase type II, AB binding alcohol dehydrogenase, Ads9, Amyloid beta binding polypeptide, Amyloid beta peptide binding alcohol dehydrogenase, Amyloid beta peptide binding protein, Endoplasmic Reticulum Amyloid Binding Protein, Endoplasmic reticulum associated amyloid beta peptide binding protein, ER associated amyloid beta-binding protein, HADH 2, HCD 2, Hydroxyacyl CoA Dehydrogenase type II, Hydroxyacyl Coenzyme A dehydrogenase type II, Hydroxysteroid (17 beta) dehydrogenase 10, Mental retardation X linked syndromic 11, Mitochondrial RNase P protein 2, DuPXp11.22, Short
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	28.1 kDa (271aa) confirmed by MALDI-TOF
Description	HSD17B10 is a member of the short-chain dehydrogenase/reductase superfamily. This mitochondrial protein catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. HSD17B10 plays an important role in processing steroid hormones and fats, and also helps break down the protein building block (amino acid) isoleucine. This enzyme is also necessary for several chemical reactions involving female sex hormones (estrogens) and male sex hormones (androgens). It is essential for maintaining appropriate levels of male and female sex hormones. This protein may contribute to the neuronal dysfunction associated with Alzheimer disease. Recombinant HSD17B10 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, and 100mM NaCl.
Antigen Species	Human
Gene Category	Redox Proteins
Domain	12-261aa
Species of Protein	Human
Manufacturer - Search Terms	HSD17B10, 3-hydroxyacyl-CoA dehydrogenase type-2, Hydroxyacyl Coenzyme A dehydrogenase type II, Mitochondrial L3 Hydroxyacyl CoA Dehydrogenase, 17 beta hydroxysteroid dehydrogenase 10, 17 beta hydroxysteroid dehydrogenase type 10, 17b HSD10, 3 hydroxy 2 methylbutyryl CoA dehydrogenase, 3 hydroxyacyl CoA dehydrogenase type 2, 3 hydroxyacyl CoA dehydrogenase type II, AB binding alcohol dehydrogenase, ABAD, Ads9, Amyloid beta binding polypeptide, Amyloid beta peptide binding alcohol dehydrogenase, Amyloid beta peptide binding protein, CAMR, DuPXp11.22, Endoplasmic Reticulum Amyloid Binding Protein, Endoplasmic reticulum associated amyloid beta peptide binding protein, ER associated amyloid beta-binding protein, ERAB, HADH 2, HADH2, HCD 2, HCD2, HSD17B10, Hydroxyacyl CoA Dehydrogenase type II, Hydroxysteroid (17 beta) dehydrogenase 10, Mental retardation X linked syndromic 11, MHBD, Mitochondrial ribonuclease P protein 2, Mitochondrial RNase P protein 2, MRPP2, MRX17, SCHAD, SDR5C1, Short,
Manufacturer - Alternative Names	Hydroxysteroid 17-beta dehydrogenase 10, HADH2, MRXS10, ERAB, SCHAD, MHBD, 17b-HSD10, ABAD, SDR5C1, MRPP2, CAMR, Hydroxyacyl-Coenzyme A dehydrogenase, type II, mental retardation, X-linked, syndromic 10, Hydroxysteroid (17-beta) dehydrogenase 10, type 10 17b-HSD, type 10 17beta-hydroxysteroid dehydrogenase, AB-binding alcohol dehydrogenase, short chain dehydrogenase/reductase family 5C, member 1, mitochondrial RNase P subunit 2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 ug

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Delivery expected until 7/31/2025

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