Comparison

Recombinant human p62/SQSTM1 protein

Item no. NKM-ATGP0532-20ug
Manufacturer NKMAX
Amount 20 ug
Quantity options 100 ug 20 ug 500 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 85% by SDS-PAGE
Sequence MAMSYVKDDI FRIYIKEKKE CRRDHRPPCA QEAPRNMVHP NVICDGCNGP VVGTRYKCSV CPDYDLCSVC EGKGLHRGHT KLAFPSPFGH LSEGFSHSRW LRKVKHGHFG WPGWEMGPPG NWSPRPPRAG EARPGPTAES ASGPSEDPSV NFLKNVGESV AAALSPLGIE VDIDVEHGGK RSRLTPVSPE SSSTEEKSSS QPSSCCSDPS KPGGNVEGAT QSLAEQMRKI AL
Citations Falchetti A., et al. (2004) J Bone Miner Res. 19(6):1013-7.
NCBI NP_001135771
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Sequestosome 1,A170,OSIL,p60,p62,p62B,PDB3,ZIP3,Sequestosome 1 EBI 3 associated protein of 60 kDa,ZIP,ZIP 3,EBI3 associated protein of 60 kDa,EBIAP,MGC127197,ORCA.M530,OSF-6,Osi,Oxidative stress induced like,Paget disease of bone 3,PDB 3,Phosphotyrosine independent ligand for the Lck SH2 domain of 62 kDa,Phosphotyrosine independent ligand for the Lck SH2 domain p62,PKC-zeta-interacting protein,Protein kinase C-zeta-interacting protein,SQSTM 1,STAP,STONE14,ubiquitin binding protein p62,
Similar products SQSTM1, p62, ATGP0532-10ug, ATGP0532-20ug, ATGP0532-50ug, ATGP0532-100ug, ATGP0532-250ug, ATGP0532-500ug, ATGP0532-1mg, ATGP0532-10, ATGP0532-20, ATGP0532-50, ATGP0532-100, ATGP0532-250, ATGP0532-500, ATGP0532-1
Available
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
39.7 kDa (364aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Description
SQSTM1 is an adapter protein which binds ubiquitin and regulates signaling cascades through ubiquitination. It may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1 and play a role in titin/TTN downstream signaling in muscle cells. This protein also may be involved in cell differentiation, apoptosis, immune response and regulation of K+ channels. Mutations in the ubiquitin-associated (uBA) domain of the sequestosome 1 protein commonly cause Paget's disease since the uBA is necessary for aggregate sequestration and cell survival. Recombinant SQSTM1 protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 1mM DTT
Antigen Species
Human
Gene Category
Signal Transduction
Domain
1-356aa
Species of Protein
Human
Manufacturer - Search Terms
p62, SQSTM1, ATGP0532-10ug, ATGP0532-20ug, ATGP0532-50ug, ATGP0532-100ug, ATGP0532-250ug, ATGP0532-500ug, ATGP0532-1mg, ATGP0532-10, ATGP0532-20, ATGP0532-50, ATGP0532-100, ATGP0532-250, ATGP0532-500, ATGP0532-1
Manufacturer - Alternative Names
Sequestosome 1, A170, OSIL, p60, p62, p62B, PDB3, ZIP3, Sequestosome 1 EBI 3 associated protein of 60 kDa, ZIP, ZIP 3, EBI3 associated protein of 60 kDa, EBIAP, MGC127197, ORCA.M530, OSF-6, Osi, Oxidative stress induced like, Paget disease of bone 3, PDB 3, Phosphotyrosine independent ligand for the Lck SH2 domain of 62 kDa, Phosphotyrosine independent ligand for the Lck SH2 domain p62, PKC-zeta-interacting protein, Protein kinase C-zeta-interacting protein, SQSTM 1, STAP, STONE14, ubiquitin binding protein p62

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 20 ug
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close