Recombinant mouse Sonic Hedgehog/Shh protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

SHH is one of three proteins in the mammalian signaling pathway family called hedgehog, the others being desert hedgehog (DHH) and Indian hedgehog (IHH). This protien is the best studied ligand of the hedgehog signaling pathway. It plays a key role in regulating vertebrate organogenesis. SHH contain amino-terminal signal peptides and apparently function as secreted proteins involved in the mediation of various cell-cell interactions. Recombinant mouse SHH protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT

Development

< 1 EU per 1ug of protein (determined by LAL method)

Sonic Hedgehog, Shh, Sonic hedgehog protein, Dsh, Hhg1, Hx, Hx13, Sonic hedgehog protein HHG 1, HHG1, HLP 3, HLP3, Holoprosencephaly 3, HPE 3, HPE3, MCOPCB5, SHH, SMMC I, SMMCI, Sonic Hedgehog (Drosophila) homolog, sonic hedgehog homolog (Drosophila), Sonic hedgehog homolog, TPT, TPTPS., ATGP0537-10ug, ATGP0537-20ug, ATGP0537-50ug, ATGP0537-100ug, ATGP0537-250ug, ATGP0537-500ug, ATGP0537-1mg, ATGP0537-10, ATGP0537-20, ATGP0537-50, ATGP0537-100, ATGP0537-250, ATGP0537-500, ATGP0537-1