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Recombinant human Calreticulin protein

Recombinant human Calreticulin protein

Item no.	NKM-ATGP0542-100ug
Manufacturer	NKMAX
Amount	100 ug
Quantity options	100 ug 20 ug 500 ug
Category	Oncology Neuroscience Molecular Targets for Neuroscience By Cell Type Hematology Leukemia Peptides & Proteins Recombinant Proteins Myelofibrosis
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 85% by SDS-PAGE
Sequence	<MGSSHHHHHH SSGLVPRGSH M>EPAVYFKEQ FLDGDGWTSR WIESKHKSDF GKFVLSSGKF YGDEEKDKGL QTSQDARFYA LSASFEPFSN KGQTLVVQFT VKHEQNIDCG GGYVKLFPNS LDQTDMHGDS EYNIMFGPDI CGPGTKKVHV IFNYKGKNVL INKDIRCKDD EFTHLYTLIV RPDNTYEVKI DNSQVESGSL EDDWDFLPPK KIKDPDASKP EDWDERAKID
Citations	Kropp LE., et al. (2010) J Immunol. 184(10):5619-27. Singh P., et al. (2010) J Biochem. 147(5):625-32.
NCBI	NP_004334.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	cC1qR,CRT,FLJ26680,RO,SSA,Autoantigen RO,CALR,CALR protein,Calregulin,Calreticulin,CRP55,CRTC,ERp60,FLJ26680,grp60,HACBP,Sicca syndrome antigen A.
Similar products	SSA, Calreticulin, CALR, CRT, FLJ26680, RO, cC1qR, ERp60, CRP55, Calregulin, HACBP, CRTC, grp60, Autoantigen RO, CALR protein, Sicca syndrome antigen A., ATGP0542-10ug, ATGP0542-20ug, ATGP0542-50ug, ATGP0542-100ug, ATGP0542-250ug, ATGP0542-500ug, ATGP0542-1mg, ATGP0542-10, ATGP0542-20, ATGP0542-50, ATGP0542-100, ATGP0542-250, ATGP0542-500, ATGP0542-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	48.7 kDa (421aa) confirmed by MALDI-TOF
Description	Calreticulin is the major calcium binding protein found in smooth muscle sarcoplasmic reticulum (SR) and non-muscle endoplasmic reticulum (ER) membranes. Calreticulin can inhibit the binding of androgen receptor to its hormone-responsive DNA element and can inhibit androgen receptor and retinoic acid receptor transcriptional activities in vivo, as well as retinoic acid-induced neuronal differentiation. Thus, Calreticulin can act as an important modulator of the regulation of gene transcription by nuclear hormone receptors. Recombinant human Calreticulin protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 0.1M Nacl, 10% glycerol
Antigen Species	Human
Gene Category	Heat Shock Proteins
Domain	18-417aa
Species of Protein	Human
Manufacturer - Search Terms	Calreticulin, cC1qR, CRT, FLJ26680, RO, SSA, Autoantigen RO, CALR, CALR protein, Calregulin, Calreticulin, CRP55, CRTC, ERp60, FLJ26680, grp60, HACBP, Sicca syndrome antigen A., ATGP0542-10ug, ATGP0542-20ug, ATGP0542-50ug, ATGP0542-100ug, ATGP0542-250ug, ATGP0542-500ug, ATGP0542-1mg, ATGP0542-10, ATGP0542-20, ATGP0542-50, ATGP0542-100, ATGP0542-250, ATGP0542-500, ATGP0542-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 7/31/2025

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