« Back
Home /
Recombinant human FHIT protein

Recombinant human FHIT protein

Item no.	NKM-ATGP0563-500ug
Manufacturer	NKMAX
Amount	500 ug
Quantity options	100 ug 20 ug 500 ug
Category	Neuroscience Aging & Neurological Disorders Peptides & Proteins Recombinant Proteins SDS-PAGE
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 95% by SDS-PAGE
Sequence	MSFRFGQHLI KPSVVFLKTE LSFALVNRKP VVPGHVLVCP LRPVERFHDL RPDEVADLFQ TTQRVGTVVE KHFHGTSLTF SMQDGPEAGQ TVKHVHVHVL PRKAGDFHRN DSIYEELQKH DKEDFPASWR SEEEMAAEAA ALRVYFQ<LEH HHHHH>
Citations	Kmiec Z., et al. (2009) J Physiol Pharmacol. 60(4):63-70. Ahmad F., et al. (2010) J Cancer Res Clin Oncol. 136(3):333-50. Kawaguchi M, et al. Synthesis of Fluorescent Probes Targeting Tumor-Suppressor Protein FHIT and Identification of Apoptosis-Inducing FHIT Inhibitors. (J Med Chem. 2021){https://pubmed.ncbi.nlm.nih.gov/34160227/}
NCBI	NP_002003
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Bis(5'-adenosyl)-triphosphatase,AP3A hydrolase,AP3Aase,Adenosine 5'-monophosphoramidase FHIT,Adenylylsulfatase,Adenylylsulfate-ammonia adenylyltransferase,Diadenosine 5',5'''-P1,P3-triphosphate hydrolase,Dinucleosidetriphosphatase,Fragile histidine triad protein,FRA3B
Similar products	FHIT, AP3Aase, FRA3B, Fragile histidine triad, Dinucleosidetriphosphatase, Fragile histidine triad protein, AP3A hydrolase fragile site 3p14.2, Bis 5' adenosyl triphosphatase, FRA 3B, Fragile histidine triad gene, Tumor suppressor protein., Diadenosine 5' 5''' P1 P3 triphosphate hydrolase, Bis (5'-adenosyl)-triphosphatase, Fragile histidine triad protein AP3A hydrolase, ATGP0563-10ug, ATGP0563-20ug, ATGP0563-50ug, ATGP0563-100ug, ATGP0563-250ug, ATGP0563-500ug, ATGP0563-1mg, ATGP0563-10, ATGP0563-20, ATGP0563-50, ATGP0563-100, ATGP0563-250, ATGP0563-500, ATGP0563-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	17.9 kDa (155aa) confirmed by MALDI-TOF
Description	FHIT (fragile histidine triad) is an enzyme that cleaves adenosine 5' PPP 5' A to yield AMP and ADP. FHIT gene encompasses the common fragile site FRA3B on chromosome 3. Alterations and deletions of the FHIT gene are strongly linked to the genesis and establishment of human tumors of the lung, cervix, breast, colon, stomach and pancreas. In normal cells, FHIT may act as a tumor suppressor. This protein physically associates with ubiquitin conjugating enzyme 9. Recombinant human FHIT, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Antigen Species	Human
Gene Category	Enzymes & Proteases
Domain	1-147aa
Species of Protein	Human
Manufacturer - Search Terms	FHIT, Fragile histidine triad protein, Bis (5'-adenosyl)-triphosphatase, AP3Aase, Fragile histidine triad protein AP3A hydrolase, AP3A hydrolase fragile site 3p14.2, Bis 5' adenosyl triphosphatase, Diadenosine 5' 5''' P1 P3 triphosphate hydrolase, Dinucleosidetriphosphatase, FRA 3B, FRA3B, Fragile histidine triad, Fragile histidine triad gene, Fragile histidine triad protein, Tumor suppressor protein., ATGP0563-10ug, ATGP0563-20ug, ATGP0563-50ug, ATGP0563-100ug, ATGP0563-250ug, ATGP0563-500ug, ATGP0563-1mg, ATGP0563-10, ATGP0563-20, ATGP0563-50, ATGP0563-100, ATGP0563-250, ATGP0563-500, ATGP0563-1
Manufacturer - Alternative Names	Bis(5'-adenosyl)-triphosphatase, AP3A hydrolase, AP3Aase, Adenosine 5'-monophosphoramidase FHIT, Adenylylsulfatase, Adenylylsulfate-ammonia adenylyltransferase, Diadenosine 5', 5'''-P1, P3-triphosphate hydrolase, Dinucleosidetriphosphatase, Fragile histidine triad protein, FRA3B

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

NKM-ATGP0563-500ug-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 500 ug

available

Delivery expected until 7/31/2025

Express Delivery: Save 3 days

Compare

Add to wishlist

Get an offer