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Recombinant human Sonic Hedgehog/Shh protein

Recombinant human Sonic Hedgehog/Shh protein

Item no.	NKM-ATGP0575-100ug
Manufacturer	NKMAX
Amount	100 ug
Quantity options	100 ug 20 ug 500 ug
Category	Oncology Neuroscience Neural Signaling By Cell Type Blastoma Sarcoma Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 95% by SDS-PAGE
Sequence	MCGPGRGFGK RRHPKKLTPL AYKQFIPNVA EKTLGASGRY EGKISRNSER FKELTPNYNP DIIFKDEENT GADRLMTQRC KDKLNALAIS VMNQWPGVKL RVTEGWDEDG HHSEESLHYE GRAVDITTSD RDRSKYGMLA RLAVEAGFDW VYYESKAHIH CSVKAENSVA AKSGG<LEHHH HHH>
Citations	Marigo V, et al. (1996) Proc Natl Acad Sci u S A. 93(18):9346-51 Kolpak A, et al. (2005) J Neurosci. 25(13):3432-41
NCBI	NP_000184
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Sonic hedgehog protein,HHG1,HLP3,HPE3,SMMCI,TPT,TPTPS,Sonic hedgehog protein HHG 1,HLP 3,Holoprosencephaly 3,HPE 3,MCOPCB5,SHH,SMMC I,SMMCI,Sonic Hedgehog (Drosophila) homolog,sonic hedgehog homolog (Drosophila),Sonic hedgehog homolog
Similar products	Sonic Hedgehog, Shh, SHH, TPT, HHG1, HLP3, HPE3, MCOPCB5, SMMCI, TPTPS, Sonic hedgehog protein, HLP 3, Sonic hedgehog homolog, Holoprosencephaly 3, HPE 3, SMMC I, Sonic Hedgehog (Drosophila) homolog, sonic hedgehog homolog (Drosophila), Sonic hedgehog protein HHG 1, ATGP0575-10ug, ATGP0575-20ug, ATGP0575-50ug, ATGP0575-100ug, ATGP0575-250ug, ATGP0575-500ug, ATGP0575-1mg, ATGP0575-10, ATGP0575-20, ATGP0575-50, ATGP0575-100, ATGP0575-250, ATGP0575-500, ATGP0575-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	20.7 kDa (183aa) confirmed by MALDI-TOF
Description	SHH, also known as Sonic hedgehog protein, is one of three proteins in the mammalian signaling pathway family called hedgehog. It plays a key role in regulating vertebrate organogenesis, such as in the growth of digits on limbs and organization of the brain. It controls cell division of adult stem cells and has been implicated in development of some cancers. Recombinant human SHH protein, fused to His-tag at C-terminus was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl
Antigen Species	Human
Gene Category	Cancer
Domain	24-197aa
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Species of Protein	Human
Manufacturer - Search Terms	Sonic Hedgehog, Shh, Sonic hedgehog protein, HHG1, HLP3, HPE3, SMMCI, TPT, TPTPS, Sonic hedgehog protein HHG 1, HLP 3, Holoprosencephaly 3, HPE 3, MCOPCB5, SHH, SMMC I, SMMCI, Sonic Hedgehog (Drosophila) homolog, sonic hedgehog homolog (Drosophila), Sonic hedgehog homolog, ATGP0575-10ug, ATGP0575-20ug, ATGP0575-50ug, ATGP0575-100ug, ATGP0575-250ug, ATGP0575-500ug, ATGP0575-1mg, ATGP0575-10, ATGP0575-20, ATGP0575-50, ATGP0575-100, ATGP0575-250, ATGP0575-500, ATGP0575-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 7/31/2025

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