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Recombinant human RUNX3/CBFA3 protein

Recombinant human RUNX3/CBFA3 protein

Item no.	NKM-ATGP0576-100ug
Manufacturer	NKMAX
Amount	100 ug
Quantity options	100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 95% by SDS-PAGE
Sequence	<MGSSHHHHHH SSGLVPRGSH> MRSMVDVLAD HAGELVRTDS PNFLCSVLPS HWRCNKTLPV AFKVVALGDV PDGTVVTVMA GNDENYSAEL RNASAVMKNQ VARFNDLRFV GRSGRGKSFT LTITVFTNPT QVATYHRAIK VTVDGPREPR RHRQK
Citations	Vogiatzi P. et al. (2006) Cancer Biol Ther. 5(4):371-4. Li QL,et al. (2002)Cell. 109(1):113-24.
NCBI	NP_004341
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Runt-related transcription factor 3,AML2,CBFA3,PEBP2aC,Runt-related transcription factor 3 Acute myeloid leukemia 2 protein,Acute myeloid leukemia gene 2,AML 2,CBF alpha 3,CBFA 3,Core binding factor alpha 3 subunit,core binding factor,Core binding factor runt domain alpha subunit 3,Core binding factor subunit alpha 3.M574,core-binding factor,FLJ34510,MGC16070,Oncogene AML 2,PEA2 alpha C,PEBP2 alpha C,Pebp2a3,Polyomavirus enhancer binding protein 2 alpha C subunit,runt domain alpha subunit 3,runt related transcription factor 3,RuNX 3,SL3 3 enhancer factor 1 alpha C subunit,SL3/AKV core binding factor alpha C subunit,Transcription factor AML2.
Similar products	RUNX3, AML2, CBFA3, Runt-related transcription factor 3, core-binding factor, FLJ34510, MGC16070, PEBP2aC, PEA2 alpha C, PEBP2 alpha C, Acute myeloid leukemia gene 2, AML 2, CBF alpha 3, CBFA 3, Core binding factor alpha 3 subunit, core binding factor, Core binding factor runt domain alpha subunit 3, Oncogene AML 2, Pebp2a3, Polyomavirus enhancer binding protein 2 alpha C subunit, runt domain alpha subunit 3, runt related transcription factor 3, SL3 3 enhancer factor 1 alpha C subunit, SL3/AKV core binding factor alpha C subunit, Runt-related transcription factor 3 Acute myeloid leukemia 2 protein, Core binding factor subunit alpha 3.M574, RuNX 3, Transcription factor AML2., ATGP0576-10ug, ATGP0576-20ug, ATGP0576-50ug, ATGP0576-100ug, ATGP0576-250ug, ATGP0576-500ug, ATGP0576-1mg, ATGP0576-10, ATGP0576-20, ATGP0576-50, ATGP0576-100, ATGP0576-250, ATGP0576-500, ATGP0576-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	17.1 kDa (155aa) confirmed by MALDI-TOF
Description	RuNX3, also known as runt-related transcription factor 3, belongs to the RuNX family that regulate the expression of genes involved in cellular differentiation and cell cycle progression. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It is a strong candidate as a gastric cancer tumor suppressor. Recombinant human RuNX3, fused to His-tag at N-terminus, protein was expressed in E. coli and purified by using conventional chromatography techniques
Concentration	0.5mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Antigen Species	Human
Gene Category	Epigenomics (Transcription & Translation)
Domain	53-186aa
Species of Protein	Human
Manufacturer - Search Terms	RUNX3, CBFA3, Runt-related transcription factor 3, AML2, CBFA3, PEBP2aC, Runt-related transcription factor 3 Acute myeloid leukemia 2 protein, Acute myeloid leukemia gene 2, AML 2, CBF alpha 3, CBFA 3, Core binding factor alpha 3 subunit, core binding factor, Core binding factor runt domain alpha subunit 3, Core binding factor subunit alpha 3.M574, core-binding factor, FLJ34510, MGC16070, Oncogene AML 2, PEA2 alpha C, PEBP2 alpha C, Pebp2a3, Polyomavirus enhancer binding protein 2 alpha C subunit, runt domain alpha subunit 3, runt related transcription factor 3, RuNX 3, SL3 3 enhancer factor 1 alpha C subunit, SL3/AKV core binding factor alpha C subunit, Transcription factor AML2., ATGP0576-10ug, ATGP0576-20ug, ATGP0576-50ug, ATGP0576-100ug, ATGP0576-250ug, ATGP0576-500ug, ATGP0576-1mg, ATGP0576-10, ATGP0576-20, ATGP0576-50, ATGP0576-100, ATGP0576-250, ATGP0576-500, ATGP0576-1
Manufacturer - Alternative Names	Runt-related transcription factor 3, AML2, CBFA3, PEBP2aC, Runt-related transcription factor 3 Acute myeloid leukemia 2 protein, Acute myeloid leukemia gene 2, AML 2, CBF alpha 3, CBFA 3, Core binding factor alpha 3 subunit, core binding factor, Core binding factor runt domain alpha subunit 3, Core binding factor subunit alpha 3.M574, core-binding factor, FLJ34510, MGC16070, Oncogene AML 2, PEA2 alpha C, PEBP2 alpha C, Pebp2a3, Polyomavirus enhancer binding protein 2 alpha C subunit, runt domain alpha subunit 3, runt related transcription factor 3, RuNX 3, SL3 3 enhancer factor 1 alpha C subunit, SL3/AKV core binding factor alpha C subunit, Transcription factor AML2.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 7/31/2025

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