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Recombinant human K-Ras protein

Recombinant human K-Ras protein

Item no.	NKM-ATGP0609-20ug
Manufacturer	NKMAX
Amount	20 ug
Quantity options	100 ug 20 ug 500 ug
Category	Oncology By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Adenocarcinoma Cytoskeleton SDS-PAGE By Organ Lung Cancer Colorectal Cancer small GTPases Ras Subfamily
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 90% by SDS-PAGE
Sequence	<MGSSHHHHHH SSGLVPRGSH> MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG HEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHHYREQI KRVKDSEDVP MVLVGNKCDL PSRTVDTKQA QDLARSYGIP FIETSAKTRQ GVDDAFYTLV REIRKHKEKM SKDGKKKKKK SKTKC
Citations	Lee W., et al. (2010) Nature. 465(7297):473-7. Singh M., et al. (2010) Nat Biotechnol. 28(6):585-93
NCBI	AAH13572.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	GTPase Kras,KRAS proto-oncogene GTPase,KRAS2,v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog,v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog,Kirsten rat sarcoma viral oncogene homolog,KRAS1,K-Ras4B,K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras,RASK2
Similar products	RASK2, K-RAS, NS3, C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, K RAS2B, K RAS4A, K RAS4B, KI RAS, KRAS 1, NS 3, GTPase Kras, ATGP0609-10ug, ATGP0609-20ug, ATGP0609-50ug, ATGP0609-100ug, ATGP0609-250ug, ATGP0609-500ug, ATGP0609-1mg, ATGP0609-10, ATGP0609-20, ATGP0609-50, ATGP0609-100, ATGP0609-250, ATGP0609-500, ATGP0609-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	23.2 kDa (205aa) confirmed by MALDI-TOF
Description	KRAS is a member of the small GTPase superfamily. This protein is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. under normal conditions, Ras family members influence cell growth and differentiation events in a subcellular membrane compartmentalization-based signaling system. Oncogenic Ras can deregulate processes that control both cell proliferation and apoptosis. Recombinant human KRAS protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration	0.5mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 1mM DTT, 10% glycerol
Antigen Species	Human
Gene Category	Cancer
Domain	1-185aa (partial)
Species of Protein	Human
Manufacturer - Search Terms	K-RAS, GTPase Kras, C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, NS3, RASK2, GTPase Kras, K-RAS2A, K RAS2B, K RAS4A, K RAS4B, KI RAS, KRAS 1, NS 3, ATGP0609-10ug, ATGP0609-20ug, ATGP0609-50ug, ATGP0609-100ug, ATGP0609-250ug, ATGP0609-500ug, ATGP0609-1mg, ATGP0609-10, ATGP0609-20, ATGP0609-50, ATGP0609-100, ATGP0609-250, ATGP0609-500, ATGP0609-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 ug

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Delivery expected until 7/31/2025

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