Comparison

Recombinant human SUMO E1/SAE1 protein

Item no. NKM-ATGP0610-10ug
Manufacturer NKMAX
Amount 10 ug
Quantity options 10 ug 250 ug 50 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS, T7 Epitope
Purity > 90% by SDS-PAGE
Sequence <MHHHHHHMAS MTGGQQMGRD LYDDDDKDRW GS>MVEKEEAG GGISEEEAAQ YDRQIRLWGL EAQKRLRASR VLLVGLKGLG AEIAKNLILA GVKGLTMLDH EQVTPEDPGA QFLIRTGSVG RNRAEASLER AQNLNPMVDV KVDTEDIEKK PESFFTQFDA VCLTCCSRDV IVKVDQICHK NSIKFFTGDV FGYHGYTFAN LGEHEFVEEK TKVAKVSQGV EDGPDTKRAK
Citations Boggio R., et al. (2007) J Biol Chem. 282(21):15376-82.
Jones MC., et al. (2006) Proc Natl Acad Sci u S A. 103(44):16272-7.
NCBI NP_005491.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias SUMO1 activating enzyme subunit 1,SUMO-activating enzyme subunit 1,Ubiquitin-like 1-activating enzyme E1A,activator Of sumo 1,AOS1,SUA1,UBLE1A
Similar products SAE1, AOS1, HSPC140, SuMO1 activating enzyme subunit 1, SuA1, uBLE1A, ubiquitin-like 1-activating enzyme E1A, AOS 1, HSPC 140, SuA 1, uBLE 1A, uBL E1A, SAE 1, ubiquitin like protein SuMO 1 activating enzyme, ATGP0610-10ug, ATGP0610-20ug, ATGP0610-50ug, ATGP0610-100ug, ATGP0610-250ug, ATGP0610-500ug, ATGP0610-1mg, ATGP0610-10, ATGP0610-20, ATGP0610-50, ATGP0610-100, ATGP0610-250, ATGP0610-500, ATGP0610-1
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Conjugate / Tag
His-T7-Tag
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
42.2 kDa (378aa) confirmed by MALDI-TOF
Description
SAE1, also known as AOS1, belongs to the ubiquitin-activating E1 family of proteins and plays an important role in the first step of the uBL1 conjugation pathway. Proteins conjugated to ub are marked for progressive degradation by the 26S Proteasome. SAE1, which is a dimeric enzyme, functions as a uBLI E1 ligase mediating the ATP-dependent activation of uBL1. This protein can bind with uBLE1A and uBLE1B to form a heterodimer which can bind uBL1. Recombinant human SAE1 protein, fused to His-T7-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Antigen Species
Human
Gene Category
Ubiquitination
Domain
1-346aa
Species of Protein
Human
Manufacturer - Search Terms
SAE1, SuMO1 activating enzyme subunit 1, AOS1, HSPC140, SuA1, uBLE1A, SuMO1 activating enzyme subunit 1, ubiquitin-like 1-activating enzyme E1A, AOS 1, HSPC 140, SuA 1, uBLE 1A, uBL E1A, SAE 1, ubiquitin like protein SuMO 1 activating enzyme, ATGP0610-10ug, ATGP0610-20ug, ATGP0610-50ug, ATGP0610-100ug, ATGP0610-250ug, ATGP0610-500ug, ATGP0610-1mg, ATGP0610-10, ATGP0610-20, ATGP0610-50, ATGP0610-100, ATGP0610-250, ATGP0610-500, ATGP0610-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 ug
Available: In stock
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