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Recombinant mouse alpha-Synuclein protein

Recombinant mouse alpha-Synuclein protein

Item no.	NKM-ATGP0619-100ug
Manufacturer	NKMAX
Amount	100 ug
Quantity options	100 ug 20 ug 500 ug
Category	Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Mouse (Murine, Mus musculus)
Host	E.coli
Conjugate/Tag	Untagged
Purity	> 95% by SDS-PAGE
Sequence	MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVTTVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGNIAA ATGFVKKDQM GKGEEGYPQE GILEDMPVDP GSEAYEMPSE EGYQDYEPEA
Citations	ueda K., et al. (1993) Proc. Natl. Acad. Sci. uSA 90:11282-11286 Kim J., et al. (1997) Molecules and Cells 7:78-83 Jakes R., et al. (1994) FEBS lett. 345:27-32. Kim S, et al. Alpha-synuclein induces migration of BV-2 microglial cells by up-regulation of CD44 and MT1-MMP. (J Neurochem. 2009){https://pubmed.ncbi.nlm.nih.gov/19457162/} Joo SH, et al. Regulation of matrix metalloproteinase-9 and tissue plasminogen activator activity by alpha-synuclein in rat primary glial cells. (Neurosci Lett. 2010){https://pubmed.ncbi.nlm.nih.gov/20026244/} Lee HJ, et al. Enzyme-linked immunosorbent assays for α-synuclein with species and multimeric state specificities. (J Neurosci Methods. 2011){https://pubmed.ncbi.nlm.nih.gov/21658411/} Park HJ, et al. Mesenchymal stem cells enhance α-synuclein clearance via M2 microglia polarization in experimental and human parkinsonian disorder. (Acta Neuropathol. 2016){https://pubmed.ncbi.nlm.nih.gov/27497943/}
NCBI	NP_033247
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	alpha-Synuclein,Snca,Syn,alpha-Synuclein,NACP,Non-A beta component of AD amyloid,Non-A4 component of amyloid precursor
Similar products	alpha-Synuclein, NACP, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, Snca, Syn, a-Synuclein, ATGP0619-10ug, ATGP0619-20ug, ATGP0619-50ug, ATGP0619-100ug, ATGP0619-250ug, ATGP0619-500ug, ATGP0619-1mg, ATGP0619-10, ATGP0619-20, ATGP0619-50, ATGP0619-100, ATGP0619-250, ATGP0619-500, ATGP0619-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	14.4 kDa (140aa) confirmed by MALDI-TOF
Description	Alpha-Synuclein, also known as SNCA, an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-Synuclein has been suggested to be implicated in the pathogenesis of Parkinson. Recombinant mouse alpha-Synuclein, was expressed in E. coli and purified by using conventional chromatography techniques
Concentration	1mg/ml (determined by BCA assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing, 10% glycerol
Antigen Species	Mouse
Gene Category	Neuroscience
Domain	1-140aa
Species of Protein	Mouse
Manufacturer - Search Terms	a-Synuclein, alpha-Synuclein, Snca, Syn, alpha-Synuclein, NACP, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, ATGP0619-10ug, ATGP0619-20ug, ATGP0619-50ug, ATGP0619-100ug, ATGP0619-250ug, ATGP0619-500ug, ATGP0619-1mg, ATGP0619-10, ATGP0619-20, ATGP0619-50, ATGP0619-100, ATGP0619-250, ATGP0619-500, ATGP0619-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 7/31/2025

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