Comparison

Recombinant human HIF-1 alpha/HIF1A protein

Item no. NKM-ATGP0647-10ug
Manufacturer NKMAX
Amount 10 ug
Quantity options 10 ug 250 ug 50 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 85% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MSFDQLSPLE SSSASPESAS PQSTVTVFQQ TQIQEPTANA TTTTATTDEL KTVTKDRMED IKILIASPSP THIHKETTSA TSSPYRDTQS RTASPNRAGK GVIEQTEKSH PRSPNVLSVA LSQRTTVPEE ELNPKILALQ NAQRKRKMEH DGSLFQAVGI GTLLQQPDDH AATTSLSWKR VKGCKSSEQN GMEQKTIILI PSDLACRLLG
Citations Okuyama H. et al., (2006) J. Biol Chem. 281(22):15554-63
NCBI NP_001521
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Hypoxia inducible factor 1 subunit alpha,Hypoxia-inducible factor 1-alpha,HIF1-alpha,ARNT-interacting protein,Basic-helix-loop-helix-PAS protein MOP1,Class E basic helix-loop-helix protein 78,bHLHe78,Member of PAS protein 1,PAS domain-containing protein 8,PASD8,MOP1
Similar products MOP1, PASD8, BHLHE78, Hypoxia-inducible factor 1-alpha, HIF1 a, ATGP0647-10ug, ATGP0647-20ug, ATGP0647-50ug, ATGP0647-100ug, ATGP0647-250ug, ATGP0647-500ug, ATGP0647-1mg, ATGP0647-10, ATGP0647-20, ATGP0647-50, ATGP0647-100, ATGP0647-250, ATGP0647-500, ATGP0647-1
Available
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
25.1 kDa (231aa) confirmed by MALDI-TOF (Real Molecular weight on SDS-PAGE will be shift up)
Description
HIF1A, identified as one of the transcription factors, has been found to play an essential role in oxygen homeostasis. This protein is a heterodimer composed of HIF-1beta subunit and one of three subunits (HIF-1A, HIF-2A or HIF-3A). The activation of HIF1A is closely associated with a variety of tumors and oncogenic pathways. HIF1A consists of DNA binding domain (DBD domain), Dimerization domain and C-terminla regulatiory domains, including two transactivation domains (TAD), an oxygen-dependent degradation (ODD) domain, and inhibitory domains. Recombinant human HIF1A (576-785) protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 1mM DTT, 10% glycerol
Antigen Species
Human
Gene Category
Epigenomics (Transcription & Translation)
Domain
576-785aa
Species of Protein
Human
Manufacturer - Search Terms
HIF1 a, Hypoxia-inducible factor 1-alpha, BHLHE78, MOP1, PASD8, Hypoxia-inducible factor 1-alpha, ATGP0647-10ug, ATGP0647-20ug, ATGP0647-50ug, ATGP0647-100ug, ATGP0647-250ug, ATGP0647-500ug, ATGP0647-1mg, ATGP0647-10, ATGP0647-20, ATGP0647-50, ATGP0647-100, ATGP0647-250, ATGP0647-500, ATGP0647-1
Manufacturer - Alternative Names
Hypoxia inducible factor 1 subunit alpha, Hypoxia-inducible factor 1-alpha, HIF1-alpha, ARNT-interacting protein, Basic-helix-loop-helix-PAS protein MOP1, Class E basic helix-loop-helix protein 78, bHLHe78, Member of PAS protein 1, PAS domain-containing protein 8, PASD8, MOP1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 ug
Available: In stock
available

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