Comparison

Recombinant human HIF-1 alpha/HIF1A protein

Item no. NKM-ATGP0730-100ug
Manufacturer NKMAX
Amount 100 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Category
Type Proteins
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 80% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MEGAGGANDK KKISSERRKE KSRDAARSRR SKESEVFYEL AHQLPLPHNV SSHLDKASVM RLTISYLRVR KLLDAGDLDI EDDMK
Citations Okuyama H., et al. (2006) J Biol Chem. 281(22):15554-63.
NCBI NP_001521.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Hypoxia inducible factor 1 subunit alpha,Hypoxia-inducible factor 1-alpha,HIF1-alpha,ARNT-interacting protein,Basic-helix-loop-helix-PAS protein MOP1,Class E basic helix-loop-helix protein 78,bHLHe78,Member of PAS protein 1,PAS domain-containing protein 8,PASD8,MOP1
Similar products MOP1, PASD8, BHLHE78, Hypoxia-inducible factor 1-alpha, HIF1 a, ATGP0730-10ug, ATGP0730-20ug, ATGP0730-50ug, ATGP0730-100ug, ATGP0730-250ug, ATGP0730-500ug, ATGP0730-1mg, ATGP0730-10, ATGP0730-20, ATGP0730-50, ATGP0730-100, ATGP0730-250, ATGP0730-500, ATGP0730-1
Available
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
11.8 kDa (105aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Description
Hypoxia-inducible factor-1 (HIF-1), identified as one of the transcription factors, has been found to play an essential role in oxygen homeostasis. HIF-1 is a heterodimer composed of HIF-1 beta subunit and one of three subunits (Hif-1 alpha, Hif-2 alpha or Hif-3 alpha). The activation of Hif-1 alpha is closely associated with a variety of tumors and oncogenic pathways. Hif-1 alpha consists of DNA binding domain (DBD domain), dimerization domain and C-terminal regulatory domains, including two transactivation domains (TAD), an oxygen-dependent degradation (ODD) domain, and inhibitory domains. Recombinant human Hif-1 alpha (1-85) protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT, 0.2M NaCl, 1mM EDTA
Antigen Species
Human
Gene Category
Epigenomics (Transcription & Translation)
Domain
1-85aa
Species of Protein
Human
Manufacturer - Search Terms
HIF1 a, Hypoxia-inducible factor 1-alpha, BHLHE78, MOP1, PASD8, Hypoxia-inducible factor 1-alpha, ATGP0730-10ug, ATGP0730-20ug, ATGP0730-50ug, ATGP0730-100ug, ATGP0730-250ug, ATGP0730-500ug, ATGP0730-1mg, ATGP0730-10, ATGP0730-20, ATGP0730-50, ATGP0730-100, ATGP0730-250, ATGP0730-500, ATGP0730-1
Manufacturer - Alternative Names
Hypoxia inducible factor 1 subunit alpha, Hypoxia-inducible factor 1-alpha, HIF1-alpha, ARNT-interacting protein, Basic-helix-loop-helix-PAS protein MOP1, Class E basic helix-loop-helix protein 78, bHLHe78, Member of PAS protein 1, PAS domain-containing protein 8, PASD8, MOP1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
available

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