Comparison

Recombinant human PD-ECGF/TYMP protein

Item no. NKM-ATGP0732-100ug
Manufacturer NKMAX
Amount 100 ug
Quantity options 100 ug 20 ug 500 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 90% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MAPPAPGDFS GEGSQGLPDP SPEPKQLPEL IRMKRDGGRL SEADIRGFVA AVVNGSAQGA QIGAMLMAIR LRGMDLEETS VLTQALAQSG QQLEWPEAWR QQLVDKHSTG GVGDKVSLVL APALAACGCK VPMISGRGLG HTGGTLDKLE SIPGFNVIQS PEQMQVLLDQ AGCCIVGQSE QLVPADGILY AARDVTATVD SLPLITASIL SK
Citations Heldin C H., et al. (1991) J Cell Biochem. 47:208-210.
Furukawa T., et al. (1992) Nature. 356:668.

Matsumae G, et al. Targeting thymidine phosphorylase as a potential therapy for bone loss associated with periprosthetic osteolysis. (BioengTransl Med. 2021){https://pubmed.ncbi.nlm.nih.gov/34589604/}
NCBI NP_001107228
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Thymidine phosphorylase,ECGF1,hPD-ECGF,MNGIE,PDECGF,TP,Gliostatin,Platelet-derived endothelial cell growth factor,TdRPase
Similar products TYMP, TP, ECGF1, MNGIE, PDECGF, hPD-ECGF, PD-ECGF, Thymidine Phosphorylase, Gliostatin, Thymidine phosphorylase, ATGP0732-10ug, ATGP0732-20ug, ATGP0732-50ug, ATGP0732-100ug, ATGP0732-250ug, ATGP0732-500ug, ATGP0732-1mg, ATGP0732-10, ATGP0732-20, ATGP0732-50, ATGP0732-100, ATGP0732-250, ATGP0732-500, ATGP0732-1
Available
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
51.3 kDa (493aa) confirmed by MALDI-TOF
Description
Thymidine phosphorylase precursor, also known TYMP, is a platelet-derived endothelial cell growth factor that catalyzes the formation of thymine and 2-deoxy-D-ribose-1-phosphate from thymidine and orthophosphate. It is an angiogenic inducer that potently stimulates the growth of endothelial cells and induces chemotaxis. Increased expression of TYMP is seen in a wide variety of different solid tumors and inflammatory diseases and is often associated with poor prognosis. Recombinant human TYMP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Antigen Species
Human
Gene Category
Growth factors
Domain
11-482aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Species of Protein
Human
Manufacturer - Search Terms
PD-ECGF, Thymidine Phosphorylase, TYMP, Thymidine phosphorylase, ECGF1, hPD-ECGF, MNGIE, PDECGF, TP, Gliostatin, Thymidine phosphorylase, ATGP0732-10ug, ATGP0732-20ug, ATGP0732-50ug, ATGP0732-100ug, ATGP0732-250ug, ATGP0732-500ug, ATGP0732-1mg, ATGP0732-10, ATGP0732-20, ATGP0732-50, ATGP0732-100, ATGP0732-250, ATGP0732-500, ATGP0732-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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