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Recombinant human SH2D1A protein

Recombinant human SH2D1A protein

Item no.	NKM-ATGP0783-100ug
Manufacturer	NKMAX
Amount	100 ug
Quantity options	100 ug 20 ug 500 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 95% by SDS-PAGE
Sequence	<MGSSHHHHHH SSGLVPRGSH> MDAVAVYHGK ISRETGEKLL LATGLDGSYL LRDSESVPGV YCLCVLYHGY IYTYRVSQTE TGSWSAETAP GVHKRYFRKI KNLISAFQKP DQGIVIPLQY PVEKKSSARS TQGTTGIRED PDVCLKAP
Citations	Schwartzberg PL., et al. (2010) Immunity. 32(2):253-65. Lenardo MJ., et al (2009) J Clin Invest. 119(10):2976-89
NCBI	NP_002342
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	SH2 domain-containing protein 1A,DSHP,EBVS,IMD5,LYP,MTCP1,SAP,XLP,XLPD
Similar products	SH2D1A, DSHP, SAP, SH2 domain-containing protein 1A, MTCP1, LYP, EBVS, IMD5, XLP, XLPD, ATGP0783-10ug, ATGP0783-20ug, ATGP0783-50ug, ATGP0783-100ug, ATGP0783-250ug, ATGP0783-500ug, ATGP0783-1mg, ATGP0783-10, ATGP0783-20, ATGP0783-50, ATGP0783-100, ATGP0783-250, ATGP0783-500, ATGP0783-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	16.3 kDa (148aa) confirmed by MALDI-TOF
Description	SH2D1A is an inhibitor of the signaling lymphocyte activation molecule (SLAM) self-association. This protein is expressed at a high level in thymus and lung, with a lower level of expression in spleen and liver. Defects in SH2D1A are a cause of X-linked lymphoproliferative disease (XLPD) also known as Duncan disease. XLPD is characterized by a rare congenital immunodeficiency following Epstein-Barr virus (EBV) infection. Recombinant human SH2D1A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4)
Antigen Species	Human
Gene Category	Immunology
Domain	1-128aa
Species of Protein	Human
Manufacturer - Search Terms	SH2D1A, SH2 domain-containing protein 1A, DSHP, EBVS, IMD5, LYP, MTCP1, SAP, XLP, XLPD, ATGP0783-10ug, ATGP0783-20ug, ATGP0783-50ug, ATGP0783-100ug, ATGP0783-250ug, ATGP0783-500ug, ATGP0783-1mg, ATGP0783-10, ATGP0783-20, ATGP0783-50, ATGP0783-100, ATGP0783-250, ATGP0783-500, ATGP0783-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 7/31/2025

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