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Recombinant human 17 beta-HSD11/HSD17B11 protein

Recombinant human 17 beta-HSD11/HSD17B11 protein

Item no.	NKM-ATGP0848-500ug
Manufacturer	NKMAX
Amount	500 ug
Quantity options	100 ug 20 ug 500 ug
Category	Metabolism Diabetes Cholesterol & Lipid Metabolism Peptides & Proteins Recombinant Proteins Lipid & Fatty Acid Transport SDS-PAGE
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 95% by SDS-PAGE
Sequence	MGSSHHHHHH SSGLVPRGSH MESFVKLFIP KRRKSVTGEI VLITGAGHGI GRLTAYEFAK LKSKLVLWDI NKHGLEETAA KCKGLGAKVH TFVVDCSNRE DIYSSAKKVK AEIGDVSILV NNAGVVYTSD LFATQDPQIE KTFEVNVLAH FWTTKAFLPA MTKNNHGHIV TVASAAGHVS VPFLLAYCSS KFAAVGFHKT LTDELAALQI TGVKTTCLCP NFVNTGFIKN PS
Citations	Rotinen M., et al. (2010) J Steroid Biochem Mol Biol. 122(4):164-71. Nakamura Y., et al. (2009) Neoplasma. 56(4):317-20.
NCBI	NP_057329
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Hydroxysteroid 17-beta dehydrogenase 11,Estradiol 17-beta-dehydrogenase 11,DHRS8,PAN1B,SDR16C2,17-beta-hydroxysteroid dehydrogenase 11. 17-beta-HSD 11,17bHSD11,17betaHSD11,17-beta-hydroxysteroid dehydrogenase XI,17-beta-HSD XI,17betaHSDXI,Cutaneous T-cell lymphoma-associated antigen HD-CL-03,CTCL-associated antigen HD-CL-03,Dehydrogenase/reductase SDR family member 8,Retinal short-chain dehydrogenase/reductase 2,retSDR2,Short chain dehydrogenase/reductase family 16C member 2
Similar products	HSD17B11, 17BHSD11, DHRS8, PAN1B, RETSDR2, SDR16C2, Estradiol 17-beta-dehydrogenase 11, 17-beta-HSD 11, 17-beta-HSD XI, 17betaHSDXI, 17betaHSD11, Dehydrogenase/reductase SDR family member 8, Retinal short-chain dehydrogenase/reductase 2, 17-beta-hydroxysteroid dehydrogenase XI, Cutaneous T-cell lymphoma-associated antigen HD-CL-03, CTCL-associated antigen HD-CL-03, 17 beta HSD 11, 17 beta HSD XI, 17 beta hydroxysteroid dehydrogenase 11, 17 beta hydroxysteroid dehydrogenase XI, 17-beta-hydroxysteroid dehydrogenase 11. 17-beta-HSD 11, CTCL associated antigen HD CL 03, CTCL associated antigen HD-CL-03, Cutaneous T cell lymphoma-associated antigen HD CL 03, Cutaneous T cell lymphoma-associated antigen HD-CL-03, Cutaneous T-cell lymphoma-associated antigen HD CL 03, Estradiol 17 beta dehydrogenase 11, Hydroxysteroid (17-beta) dehydrogenase 11, Hydroxysteroid 17 beta dehydrogenase 11, Hydroxysteroid 17-beta dehydrogenase 11, Retinal short chain dehydrogenase/reductase 2, Short chain dehydrog
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	31.4 kDa (287aa) confirmed by MALDI-TOF
Description	HSD17B11, also known as DHRS8 (dehydrogenase/reductase SDR family member 8), belongs to the HSD17B family of proteins, which regulate the availability of steroids within various tissues throughout the body. It is widely expressed with highest levels found in retina, pancreas, kidney, liver, lung, adrenal, small intestine, ovary and heart as well as in steroidogenic cells. This protein converts androstan-3-alpha, 17-beta-diol (3-alpha-diol) to androsterone, suggesting it may participate in androgen metabolism during steroidogenesis. Recombinant human HSD17B11 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration	0.5mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 5mM DTT, 20% glycerol
Antigen Species	Human
Gene Category	Enzymes & Proteases
Domain	20-285aa
Species of Protein	Human
Manufacturer - Search Terms	17 beta HSD 11, 17 beta HSD XI, 17 beta hydroxysteroid dehydrogenase 11, 17 beta hydroxysteroid dehydrogenase XI, 17-beta-HSD 11, 17-beta-HSD XI, 17betaHSD11, 17betaHSDXI, 17-beta-hydroxysteroid dehydrogenase 11. 17-beta-HSD 11, 17-beta-hydroxysteroid dehydrogenase XI, 17BHSD11, CTCL associated antigen HD CL 03, CTCL associated antigen HD-CL-03, CTCL-associated antigen HD-CL-03, Cutaneous T cell lymphoma-associated antigen HD CL 03, Cutaneous T cell lymphoma-associated antigen HD-CL-03, Cutaneous T-cell lymphoma-associated antigen HD CL 03, Cutaneous T-cell lymphoma-associated antigen HD-CL-03, Dehydrogenase/reductase SDR family member 8, DHRS8, Estradiol 17 beta dehydrogenase 11, Estradiol 17-beta-dehydrogenase 11, HSD17B11, Hydroxysteroid (17-beta) dehydrogenase 11, Hydroxysteroid 17 beta dehydrogenase 11, Hydroxysteroid 17-beta dehydrogenase 11, PAN1B, Retinal short chain dehydrogenase/reductase 2, Retinal short-chain dehydrogenase/reductase 2, RETSDR2, SDR16C2, Short chain dehydrog
Manufacturer - Alternative Names	Hydroxysteroid 17-beta dehydrogenase 11, Estradiol 17-beta-dehydrogenase 11, DHRS8, PAN1B, SDR16C2, 17-beta-hydroxysteroid dehydrogenase 11. 17-beta-HSD 11, 17bHSD11, 17betaHSD11, 17-beta-hydroxysteroid dehydrogenase XI, 17-beta-HSD XI, 17betaHSDXI, Cutaneous T-cell lymphoma-associated antigen HD-CL-03, CTCL-associated antigen HD-CL-03, Dehydrogenase/reductase SDR family member 8, Retinal short-chain dehydrogenase/reductase 2, retSDR2, Short chain dehydrogenase/reductase family 16C member 2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 7/31/2025

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