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Recombinant human CRKL protein

Recombinant human CRKL protein

Item no.	NKM-ATGP0857-20ug
Manufacturer	NKMAX
Amount	20 ug
Quantity options	100 ug 20 ug 500 ug
Category	Oncology Neuroscience Molecular Targets for Neuroscience By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins SDS-PAGE
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 90% by SDS-PAGE
Sequence	<MGSSHHHHHH SSGLVPRGSH> MSSARFDSSD RSAWYMGPVS RQEAQTRLQG QRHGMFLVRD SSTCPGDYVL SVSENSRVSH YIINSLPNRR FKIGDQEFDH LPALLEFYKI HYLDTTTLIE PAPRYPSPPM GSVSAPNLPT AEDNLEYVRT LYDFPGNDAE DLPFKKGEIL VIIEKPEEQW WSARNKDGRV GMIPVPYVEK LVRSSPHGKH GNRNSNSYGI PEPAHAYAQP
Citations	Arai A., et al. (2001) J Biol Chem. 276(35):33282-90. Senechal K., et al. (1996) J Biol Chem. 271(38):23255-61.
NCBI	NP_005198.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CRK like proto-oncogene,Adaptor protein,V-crk avian sarcoma virus CT10 oncogene homolog-like
Similar products	CrkL, Crk-like protein, ATGP0857-10ug, ATGP0857-20ug, ATGP0857-50ug, ATGP0857-100ug, ATGP0857-250ug, ATGP0857-500ug, ATGP0857-1mg, ATGP0857-10, ATGP0857-20, ATGP0857-50, ATGP0857-100, ATGP0857-250, ATGP0857-500, ATGP0857-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	35.9 kDa (323aa) confirmed by MALDI-TOF
Description	CRKL is a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JuN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substitutete of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and has oncogenic potential. Recombinant human CRKL protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl.
Antigen Species	Human
Gene Category	Cancer
Domain	1-303aa
Species of Protein	Human
Manufacturer - Search Terms	CrkL, Crk-like protein, ATGP0857-10ug, ATGP0857-20ug, ATGP0857-50ug, ATGP0857-100ug, ATGP0857-250ug, ATGP0857-500ug, ATGP0857-1mg, ATGP0857-10, ATGP0857-20, ATGP0857-50, ATGP0857-100, ATGP0857-250, ATGP0857-500, ATGP0857-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 ug

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Delivery expected until 10/2/2025

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