Recombinant human SGT1/SUGT1 protein

Proteins

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

SuGT1, also known as suppressor of G2 allele of SKP1, is a homolog of the yeast protein SGT1, a regulator of the cell cycle that is essential for G1/S and G2/M transitions. It contains a CS domain, a SGS domain, a p23 domain and three tetratricopeptide repeats (TPR). This protein associates with Skp1 p19 and CuL-1, subunits of the SCF ubiquitin ligase complex, and is thought to play a role in protein degradation. In addition, it is required for the kinetochores assembly, and has function as a co-chaperone for HSP90. Recombinant human SuGT1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol 1mM DTT, 0.1M NaCl

Cell Cycle

Human

MIS12 kinetochore complex assembly cochaperone, Protein 40-6-3, Protein SGT1 homolog, SGT1, SGT1 homolog, SUGT1, Suppressor of G2 allele of SKP1 homolog isoform SGT1B, ATGP0899-10ug, ATGP0899-20ug, ATGP0899-50ug, ATGP0899-100ug, ATGP0899-250ug, ATGP0899-500ug, ATGP0899-1mg, ATGP0899-010, ATGP0899-020, ATGP0899-050, ATGP0899-100, ATGP0899-250, ATGP0899-500, ATGP0899-01M