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Recombinant human UROS protein

Recombinant human UROS protein

Item no.	NKM-ATGP1066-500ug
Manufacturer	NKMAX
Amount	500 ug
Quantity options	100 ug 20 ug 500 ug
Category	Metabolism Cholesterol & Lipid Metabolism Peptides & Proteins Recombinant Proteins SDS-PAGE Enzymes Prostaglandin Synthases
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 95% by SDS-PAGE
Sequence	<MGSSHHHHHH SSGLVPRGSH> MKVLLLKDAK EDDCGQDPYI RELGLYGLEA TLIPVLSFEF LSLPSFSEKL SHPEDYGGLI FTSPRAVEAA ELCLEQNNKT EVWERSLKEK WNAKSVYVVG NATASLVSKI GLDTEGETCG NAEKLAEYIC SRESSALPLL FPCGNLKREI LPKALKDKGI AMESITVYQT VAHPGIQGNL NSYYSQQGVP ASITFFSPSG LTYSLKHIQE
Citations	Geronimi F. et al. (2003) J. Mol. Med. 81: 310-320. Omata Y. et al. (2004) J. BioChem. 136: 211-220.
NCBI	NP_000366
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	uroporphyrinogen-III synthase,uroporphyrinogen III synthase
Similar products	UROS, uroporphyrinogen III synthase, uroporphyrinogen-III synthase, ATGP1066-10ug, ATGP1066-20ug, ATGP1066-50ug, ATGP1066-100ug, ATGP1066-250ug, ATGP1066-500ug, ATGP1066-1mg, ATGP1066-10, ATGP1066-20, ATGP1066-50, ATGP1066-100, ATGP1066-250, ATGP1066-500, ATGP1066-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	30.7 kDa (285aa) confirmed by MALDI-TOF
Description	uROS, also known as uroporphyrinogen III synthase, is an enzyme involved in the fourth step of porphyrin metabolism, involved in the conversion of hydroxymethyl bilane into uroporphyrinogen III. Defects in this protein can cause molecular lesions that lead to the autosomal recessive Gunther disease, also known as congenital erythropoietic porphyria (CEP). Recombinant human uROS protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.1M NaCl
Antigen Species	Human
Gene Category	Enzymes & Proteases
Domain	1-265aa
Species of Protein	Human
Manufacturer - Search Terms	UROS, uroporphyrinogen-III synthase, uroporphyrinogen III synthase, ATGP1066-10ug, ATGP1066-20ug, ATGP1066-50ug, ATGP1066-100ug, ATGP1066-250ug, ATGP1066-500ug, ATGP1066-1mg, ATGP1066-10, ATGP1066-20, ATGP1066-50, ATGP1066-100, ATGP1066-250, ATGP1066-500, ATGP1066-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 7/31/2025

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