Comparison

Recombinant human POMC protein

Item no. NKM-ATGP1088-250ug
Manufacturer NKMAX
Amount 250 ug
Quantity options 10 ug 250 ug 50 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 85% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH M>WCLESSQCQ DLTTESNLLE CIRACKPDLS AETPMFPGNG DEQPLTENPR KYVMGHFRWD RFGRRNSSSS GSSGAGQKRE DVSAGEDCGP LPEGGPEPRS DGAKPGPREG KRSYSMEHFR WGKPVGKKRR PVKVYPNGAE DESAEAFPLE FKRELTGQRL REGDGPDGPA DDGAGAQADL EHSLLVAAEK KDEGPYRMEH FRWGSPPKDK
Citations Grassel S., et al. (2009) Arthritis Rheum. 60:3017-3027.
Belgardt B F., et al. (1992) J Physiol. 587:5305-5314.
NCBI NP_001030333
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Pro-opiomelanocortin preproprotein,ACTH,CLIP,LPH,MSH,NPP,POC
Similar products POMC, ATGP1088-10ug, ATGP1088-20ug, ATGP1088-50ug, ATGP1088-100ug, ATGP1088-250ug, ATGP1088-500ug, ATGP1088-1mg, ATGP1088-10, ATGP1088-20, ATGP1088-50, ATGP1088-100, ATGP1088-250, ATGP1088-500, ATGP1088-1
Available
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
28.9 kDa (262aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Description
Pro-opiomelanocortin preproprotein, also known as POMC, a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. It regulates the corticosteroid production in the adrenal cortex. Also, POMC is cleaved into ten hormone chains named NPP, gamma-MSH, ACTH, alpha-MSH, CLIP, Lipotropin beta, Lipotropin gamma, beta-MSH, beta endorphin and Met-enkephalin. Defects in the gene that encodes POMC are the cause of POMC deficiency, which is characterized by red hair and adrenal insufficiency. Recombinant human POMC protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.5) containing 1mM DTT, 50% glycerol, 0.2M NaCl, 0.1mM PMSF, 100mM Imidazole
Antigen Species
Human
Gene Category
Metabolism
Domain
27-267aa
Species of Protein
Human
Manufacturer - Search Terms
POMC, ATGP1088-10ug, ATGP1088-20ug, ATGP1088-50ug, ATGP1088-100ug, ATGP1088-250ug, ATGP1088-500ug, ATGP1088-1mg, ATGP1088-10, ATGP1088-20, ATGP1088-50, ATGP1088-100, ATGP1088-250, ATGP1088-500, ATGP1088-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 250 ug
Available: In stock
available

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