Comparison

Recombinant human TRANCE/RANK L/TNFSF11 protein

Item no. NKM-ATGP1093-20ug
Manufacturer NKMAX
Amount 20 ug
Quantity options 100 ug 20 ug 500 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 80% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MIRAEKAMVD GSWLDLAKRS KLEAQPFAHL TINATDIPSG SHKVSLSSWY HDRGWAKISN MTFSNGKLIV NQDGFYYLYA NICFRHHETS GDLATEYLQL MVYVTKTSIK IPSSHTLMKG GSTKYWSGNS EFHFYSINVG GFFKLRSGEE ISIEVSNPSL LDPDQDATYF GAFKVRDID
Citations Lam J., et al. (2001) J. Clin. Invest. 108:971-979
Ito S., et al. (2002) J. Biol. Chem. 277:6631-6636
NCBI NP_003692
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Tumor necrosis factor ligand superfamily member 11,Osteoclast differentiation factor,ODF,Osteoprotegerin ligand,OPGL,Receptor activator of nuclear factor kappa-B ligand,RANKL,TNF-related activation-induced cytokine,TRANCE,CD254
Similar products TNFSF11, RANKL, OPGL, TRANCE, Tumor necrosis factor ligand superfamily member 11, RANK L, ATGP1093-10ug, ATGP1093-20ug, ATGP1093-50ug, ATGP1093-100ug, ATGP1093-250ug, ATGP1093-500ug, ATGP1093-1mg, ATGP1093-10, ATGP1093-20, ATGP1093-50, ATGP1093-100, ATGP1093-250, ATGP1093-500, ATGP1093-1
Available
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
22.3 kDa (199aa) confirmed by MALDI-TOF
Description
TNFSF11, also known as RANKL, is a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. TNFSF11 also has a function in the immune system, where it is expressed by T helper cells and is thought to be involved in dendritic cell maturation. TNFSF11 is important in bone metabolism. This natural and necessary surface-bound molecule (also known as CD254) found on osteoblasts serves to activate osteoclasts, which are the cells involved in bone resorption. Recombinant human TNFSF11 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Antigen Species
Human
Gene Category
Immunology
Domain
140-317aa
Species of Protein
Human
Manufacturer - Search Terms
TRANCE , TNFSF11, RANK L, Tumor necrosis factor ligand superfamily member 11, OPGL, RANKL, ATGP1093-10ug, ATGP1093-20ug, ATGP1093-50ug, ATGP1093-100ug, ATGP1093-250ug, ATGP1093-500ug, ATGP1093-1mg, ATGP1093-10, ATGP1093-20, ATGP1093-50, ATGP1093-100, ATGP1093-250, ATGP1093-500, ATGP1093-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 20 ug
Available: In stock
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