Comparison

Recombinant human Oncostatin M/OSM protein

Item no. NKM-ATGP1123-20ug
Manufacturer NKMAX
Amount 20 ug
Quantity options 100 ug 20 ug 500 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 95% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MAAIGSCSKE YRVLLGQLQK QTDLMQDTSR LLDPYIRIQG LDVPKLREHC RERPGAFPSE ETLRGLGRRG FLQTLNATLG CVLHRLADLE QRLPKAQDLE RSGLNIEDLE KLQMARPNIL GLRNNIYCMA QLLDNSDTAE PTKAGRGASQ PPTPTPASDA FQRKLEGCRF LHGYHRFMHS VGRVFSKWGE SPNRSRRHSP HQALRKGVRR
Citations Nair B.C., et al. (1992) Science. 255:1430-1432
Miles S.A., et al. (1992) Science. 255:1432-1434
NCBI NP_065391
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Oncostatin M,MGC20461,Oncostatin M precursor
Similar products OSM, Oncostatin M, MGC20461, Oncostatin M precursor, ATGP1123-10ug, ATGP1123-20ug, ATGP1123-50ug, ATGP1123-100ug, ATGP1123-250ug, ATGP1123-500ug, ATGP1123-1mg, ATGP1123-10, ATGP1123-20, ATGP1123-50, ATGP1123-100, ATGP1123-250, ATGP1123-500, ATGP1123-1
Available
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
25.9 kDa (230aa) confirmed by MALDI-TOF
Description
OSM, also known as Oncostatin M, is a pleiotropic cytokine that belongs to the interleukin 6 group of cytokines. Of these cytokines it most closely resembles leukemia inhibitory factor (LIF) in both structure and function. However, it is as yet poorly defined and is proving important in liver development, haematopoeisis, inflammation and possibly CNS development. It is also associated with bone formation and destruction. OSM signals through cell surface receptors that contain the protein gp130. The type I receptor is composed of gp130 and LIFR, the type II receptor is composed of gp130 and OSMR. Recombinant human OSM protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT
Antigen Species
Human
Gene Category
Hormones & Cytokines
Domain
26-234aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Species of Protein
Human
Manufacturer - Search Terms
Oncostatin M, OSM, Oncostatin M, MGC20461, Oncostatin M precursor, ATGP1123-10ug, ATGP1123-20ug, ATGP1123-50ug, ATGP1123-100ug, ATGP1123-250ug, ATGP1123-500ug, ATGP1123-1mg, ATGP1123-10, ATGP1123-20, ATGP1123-50, ATGP1123-100, ATGP1123-250, ATGP1123-500, ATGP1123-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 20 ug
Available: In stock
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