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Recombinant human GCSH protein

Recombinant human GCSH protein

Item no.	NKM-ATGP1281-100ug
Manufacturer	NKMAX
Amount	100 ug
Quantity options	100 ug 20 ug 500 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 95% by SDS-PAGE
Sequence	<MGSSHHHHHH SSGLVPRGSH MGSM>SVRKFT EKHEWVTTEN GIGTVGISNF AQEALGDVVY CSLPEVGTKL NKQDEFGALE SVKAASELYS PLSGEVTEIN EALAENPGLV NKSCYEDGWL IKMTLSNPSE LDELMSEEAY EKYIKSIEE
Citations	Kure S., et al. (2001) J Hum Genet. 46(7):378-84. Kovata H., et al. (1991) Am J Hum Genet. 48(2):351-61.
NCBI	NP_004474
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Glycine cleavage system protein H (aminomethyl carrier),GCE,NKH
Similar products	GCSH, GCE, NKH, Glycine cleavage system protein H (aminomethyl carrier), ATGP1281-10ug, ATGP1281-20ug, ATGP1281-50ug, ATGP1281-100ug, ATGP1281-250ug, ATGP1281-500ug, ATGP1281-1mg, ATGP1281-10, ATGP1281-20, ATGP1281-50, ATGP1281-100, ATGP1281-250, ATGP1281-500, ATGP1281-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	16.4 kDa (149aa) confirmed by MALDI-TOF
Description	The enzyme system for cleavage of glycine (glycine cleavage system) is composed of four mitochondrial protein components: P protein, H protein, T protein, and L protein. GCSH is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Recombinant human GCSH protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.15M NaCl.
Antigen Species	Human
Gene Category	Metabolism
Domain	49-173aa
Species of Protein	Human
Manufacturer - Search Terms	GCSH, Glycine cleavage system protein H (aminomethyl carrier), GCE, NKH, ATGP1281-10ug, ATGP1281-20ug, ATGP1281-50ug, ATGP1281-100ug, ATGP1281-250ug, ATGP1281-500ug, ATGP1281-1mg, ATGP1281-10, ATGP1281-20, ATGP1281-50, ATGP1281-100, ATGP1281-250, ATGP1281-500, ATGP1281-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 9/4/2025

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