Comparison

Recombinant human NKIRAS1 protein

Item no. NKM-ATGP1412-10ug
Manufacturer NKMAX
Amount 10 ug
Quantity options 10 ug 50 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 85% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH> MGKGCKVVVC GLLSVGKTAI LEQLLYGNHT IGMEDCETME DVYMASVETD RGVKEQLHLY DTRGLQEGVE LPKHYFSFAD GFVLVYSVNN LESFQRVELL KKEIDKFKDK KEVAIVVLGN KIDLSEQRQV DAEVAQQWAK SEKVRLWEVT VTDRKTLIEP FTLLASKLSQ PQSKSSFPLP GRKNKGNSNS EN
Citations Fenwick C., et al. (2000) Science. 287:869-873
Chen Y., et al. (2003) J. Biol. Chem. 278:23101-23106
NCBI NP_065078.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias NF-kappa-B inhibitor-interacting Ras-like protein 1,kappaB-Ras1,KBRAS1
Similar products NKIRAS1, KBRAS1, NF-kappa-B inhibitor-interacting Ras-like protein 1, kappaB-Ras1, ATGP1412-10ug, ATGP1412-20ug, ATGP1412-50ug, ATGP1412-100ug, ATGP1412-250ug, ATGP1412-500ug, ATGP1412-1mg, ATGP1412-10, ATGP1412-20, ATGP1412-50, ATGP1412-100, ATGP1412-250, ATGP1412-500, ATGP1412-1
Available
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
23.8 kDa (212aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Description
NKIRAS1, also known as NF-kappa-B inhibitor-interacting Ras-like protein 1, belongs to the small GTPase superfamily. NKIRAS1 is atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. It may act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB. Recombinant human NKIRAS1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration
0.25mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT
Antigen Species
Human
Gene Category
Signal Transduction
Domain
1-192aa
Species of Protein
Human
Manufacturer - Search Terms
NKIRAS1, NF-kappa-B inhibitor-interacting Ras-like protein 1, kappaB-Ras1, KBRAS1, ATGP1412-10ug, ATGP1412-20ug, ATGP1412-50ug, ATGP1412-100ug, ATGP1412-250ug, ATGP1412-500ug, ATGP1412-1mg, ATGP1412-10, ATGP1412-20, ATGP1412-50, ATGP1412-100, ATGP1412-250, ATGP1412-500, ATGP1412-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 ug
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close