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Recombinant human TARS1 protein

Recombinant human TARS1 protein

Item no.	NKM-ATGP1417-50ug
Manufacturer	NKMAX
Amount	50 ug
Quantity options	100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Category	Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Protein Aggregation, Clearance & Misfolding Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 85% by SDS-PAGE
Sequence	<MGSSHHHHHH SSGLVPRGSH> MFEEKASSPS GKMGGEEKPI GAGEEKQKEG GKKKNKEGSG DGGRAELNPW PEYIYTRLEM YNILKAEHDS ILAEKAEKDS KPIKVTLPDG KQVDAESWKT TPYQIACGIS QGLADNTVIA KVNNVVWDLD RPLEEDCTLE LLKFEDEEAQ AVYWHSSAHI MGEAMERVYG GCLCYGPPIE NGFYYDMYLE EGGVSSNDFS SLEALCKKII
Citations	Freist W, et al. (1995). Biol. Chem. Hoppe-Seyler 376 (4): 213-24. Pan F, et al. (1982). Int. J. Pept. Protein Res. 20 (2): 159-66. Wang W, et al. The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity. (Nat Med. 2016){https://pubmed.ncbi.nlm.nih.gov/27348499/}
NCBI	NP_689508
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	threonyl-tRNA synthetase cytoplasmic,threonyl-tRNA synthetase,cytoplasmic,ThrRS
Similar products	TDP43, TARDBP, cytoplasmic, ThrRS, threonyl-tRNA synthetase, threonyl-tRNA synthetase cytoplasmic, ATGP1417-10ug, ATGP1417-20ug, ATGP1417-50ug, ATGP1417-100ug, ATGP1417-250ug, ATGP1417-500ug, ATGP1417-1mg, ATGP1417-10, ATGP1417-20, ATGP1417-50, ATGP1417-100, ATGP1417-250, ATGP1417-500, ATGP1417-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	85.6 kDa (743aa)
Description	TARS (Threonyl-tRNA synthetase, cytoplasmic) belongs to the class-II aminoacyl-tRNA synthetase family. This protein has its main role in tRNA aminoacylation. The N-terminal domain of the enzyme is responsible for the competition with the ribosome whilst the catalytic and the C-terminal domain are involved in binding the two anticodon arm-like structures in the operator. Recombinant human TARS protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration	0.5mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 150mM NaCl
Antigen Species	Human
Gene Category	Metabolism
Domain	1-723aa
Species of Protein	Human
Manufacturer - Search Terms	TDP43, TARDBP, threonyl-tRNA synthetase cytoplasmic, threonyl-tRNA synthetase, cytoplasmic, ThrRS, ATGP1417-10ug, ATGP1417-20ug, ATGP1417-50ug, ATGP1417-100ug, ATGP1417-250ug, ATGP1417-500ug, ATGP1417-1mg, ATGP1417-10, ATGP1417-20, ATGP1417-50, ATGP1417-100, ATGP1417-250, ATGP1417-500, ATGP1417-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 7/31/2025

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