Comparison

Recombinant human Bcl-10 protein

Item no. NKM-ATGP1457-50ug
Manufacturer NKMAX
Amount 50 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 85% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH MGSH>MEPTAP SLTEEDLTEV KKDALENLRV YLCEKIIAER HFDHLRAKKI LSREDTEEIS CRTSSRKRAG KLLDYLQENP KGLDTLVESI RREKTQNFLI QKITDEVLKL RNIKLEHLKG LKCSSCEPFP DGATNNLSRS NSDESNFSEK LRASTVMYHP EGESSTTPFF STNSSLNLPV LEVGRTENTI FSSTTLPRPG DPGAPPLPPD
Citations Rebeaud F., et al. (2008) Nat. Immunol. 9:272-281
Yui D., et al. (2001) Oncogene. 20:4317-4323
NCBI NP_003912
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias B cell CLL/lymphoma 10,BCL10,Immune signaling adaptor,CARMEN,CIPER,mE10,c-E10,CLAP
Similar products BCL10, CARMEN, CIPER, CLAP, c-E10, mE10, B cell CLL/lymphoma 10, c E10, B-cell lymphoma/leukemia 10, IMD37, Immune signaling adaptor, B cell lymphoma/leukemia 10, Ce10, ATGP1457-10ug, ATGP1457-20ug, ATGP1457-50ug, ATGP1457-100ug, ATGP1457-250ug, ATGP1457-500ug, ATGP1457-1mg, ATGP1457-010, ATGP1457-020, ATGP1457-050, ATGP1457-100, ATGP1457-250, ATGP1457-500, ATGP1457-01M
Available
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
28.8 kDa (257aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Description
BCL10, also known as B-cell lymphoma/leukemia 10, contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. It is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Recombinant human BCL10 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.05M NaCl, 1mM DTT
Antigen Species
Human
Gene Category
Signal Transduction
Domain
1-233aa
Species of Protein
Human
Manufacturer - Search Terms
, B cell CLL/lymphoma 10, B-cell lymphoma/leukemia 10, BCL10, CARMEN, c-E10, CIPER, CLAP, IMD37, Immune signaling adaptor, mE10, B cell lymphoma/leukemia 10, c E10, Ce10, ATGP1457-10ug, ATGP1457-20ug, ATGP1457-50ug, ATGP1457-100ug, ATGP1457-250ug, ATGP1457-500ug, ATGP1457-1mg, ATGP1457-010, ATGP1457-020, ATGP1457-050, ATGP1457-100, ATGP1457-250, ATGP1457-500, ATGP1457-01M

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
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