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Recombinant human ERCC1 protein

Recombinant human ERCC1 protein

Item no.	NKM-ATGP1546-10ug
Manufacturer	NKMAX
Amount	10 ug
Quantity options	10 ug 250 ug 50 ug
Category	Oncology By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins SDS-PAGE
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 90% by SDS-PAGE
Sequence	<MGSSHHHHHH SSGLVPRGSH MGSH>MDPGKD KEGVPQPSGP PARKKFVIPL DEDEVPPGVA KPLFRSTQSL PTVDTSAQAA PQTYAEYAIS QPLEGAGATC PTGSEPLAGE TPNQALKPGA KSNSIIVSPR QRGNPVLKFV RNVPWEFGDV IPDYVLGQST CALFLSLRYH NLHPDYIHGR LQSLGKNFAL RVLLVQVDVK DPQQALKELA KMCILADCTL ILAWSPEEAG
Citations	van Duin M., et al. (1986) Cell. 44:913-923 Grimwood J., et al. (2004) Nature. 428:529-535
NCBI	NP_001159521.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	DNA excision repair protein ERCC-1,COFS4,RAD10,uV20
Similar products	ERCC1, DNA excision repair protein ERCC-1, RAD10, COFS4, uV20, ATGP1546-10ug, ATGP1546-20ug, ATGP1546-50ug, ATGP1546-100ug, ATGP1546-250ug, ATGP1546-500ug, ATGP1546-1mg, ATGP1546-10, ATGP1546-20, ATGP1546-50, ATGP1546-100, ATGP1546-250, ATGP1546-500, ATGP1546-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	32.5 kDa (297aa) confirmed by MALDI-TOF
Description	ERCC1, also known as DNA excision repair protein ERCC-1, functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by uV light or formed by electrophilic compounds including cisplatin. Defects in ERCC1 are the cause of cerebro-oculo-facio-skeletal syndrome type 4 (COFS4). Recombinant human ERCC1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration	0.5mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Antigen Species	Human
Gene Category	Cancer
Domain	1-273aa
Species of Protein	Human
Manufacturer - Search Terms	ERCC1, DNA excision repair protein ERCC-1, COFS4, RAD10, uV20, ATGP1546-10ug, ATGP1546-20ug, ATGP1546-50ug, ATGP1546-100ug, ATGP1546-250ug, ATGP1546-500ug, ATGP1546-1mg, ATGP1546-10, ATGP1546-20, ATGP1546-50, ATGP1546-100, ATGP1546-250, ATGP1546-500, ATGP1546-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 7/31/2025

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