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Recombinant human NPM1 protein

Recombinant human NPM1 protein

Item no.	NKM-ATGP1576-20ug
Manufacturer	NKMAX
Amount	20 ug
Quantity options	100 ug 20 ug 500 ug
Category	Oncology Neuroscience Molecular Targets for Neuroscience By Cell Type Carcinoma Hematology Leukemia Lymphoma Sarcoma Peptides & Proteins Recombinant Proteins Adenocarcinoma SDS-PAGE
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 85% by SDS-PAGE
Sequence	<MGSSHHHHHH SSGLVPRGSH> MEDSMDMDMS PLRPQNYLFG CELKADKDYH FKVDNDENEH QLSLRTVSLG AGAKDELHIV EAEAMNYEGS PIKVTLATLK MSVQPTVSLG GFEITPPVVL RLKCGSGPVH ISGQHLVAVE EDAESEDEEE EDVKLLSISG KRSAPGGGSK VPQKKVKLAA DEDDDDDDEE DDDEDDDDDD FDDEEAEEKA PVKKSIRDTP AKNAQKSNQN
Citations	Sagawa,F., et al. (2011) EMBO J. 30 (19), 3994-4005. Neubauer,A., et al. (2011) Exp. Hematol. 39 (10), 1030-1042. Nakatomi K,et al. TLR4/MD-2 is a receptor for extracellular nucleophosmin 1. (Biomed Rep. 2021){https://pubmed.ncbi.nlm.nih.gov/33335727/}
NCBI	NP_002511.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Nucleophosmin,B23,NPM
Similar products	NPM1, ATGP1576-10ug, ATGP1576-20ug, ATGP1576-50ug, ATGP1576-100ug, ATGP1576-250ug, ATGP1576-500ug, ATGP1576-1mg, ATGP1576-10, ATGP1576-20, ATGP1576-50, ATGP1576-100, ATGP1576-250, ATGP1576-500, ATGP1576-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	34.7 kDa (314aa) confirmed by MALDI-TOF
Description	NPM1 is a phosphoprotein which moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in NPM1 are associated with acute myeloid leukemia. Recombinant human NPM1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration	0.5mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.15M NaCl, 1mM DTT
Antigen Species	Human
Gene Category	Epigenomics (Transcription & Translation)
Domain	1-294aa
Species of Protein	Human
Manufacturer - Search Terms	NPM1, ATGP1576-10ug, ATGP1576-20ug, ATGP1576-50ug, ATGP1576-100ug, ATGP1576-250ug, ATGP1576-500ug, ATGP1576-1mg, ATGP1576-10, ATGP1576-20, ATGP1576-50, ATGP1576-100, ATGP1576-250, ATGP1576-500, ATGP1576-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 ug

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Delivery expected until 7/31/2025

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