Comparison

Recombinant human RYBP protein

Item no. NKM-ATGP1600-4ug
Manufacturer NKMAX
Amount 4 ug
Quantity options 100 ug 20 ug 4 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 85% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MGSHMTMGDK KSPTRPKRQA KPAADEGFWD CSVCTFRNSA EAFKCSICDV RKGTSTRKPR INSQLVAQQV AQQYATPPPP KKEKKEKVEK QDKEKPEKDK EISPSVTKKN TNKKTKPKSD ILKDPPSEAN SIQSANATTK TSETNHTSRP RLKNVDRSTA QQLAVTVGNV TVIITDFKEK TRSSSTSSST VTSSAGSEQQ NQSSSGSEST DK
Citations Chen D, et al. (2008) EMBO Rep. 10(2):166-72.
Zheng L., et al. (2001) J. Biol. Chem. 276:31945-31952
NCBI NP_036366
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias RING1 and YY1 binding protein,AAP1,DEDAF,YEAF1
Similar products DEDAF, RYBP, YEAF1, AAP1, RING1 and YY1 binding protein, ATGP1600-10ug, ATGP1600-20ug, ATGP1600-50ug, ATGP1600-100ug, ATGP1600-250ug, ATGP1600-500ug, ATGP1600-1mg, ATGP1600-10, ATGP1600-20, ATGP1600-50, ATGP1600-100, ATGP1600-250, ATGP1600-500, ATGP1600-1
Available
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
27.4 kDa (252aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Description
RYBP (RING1- and YY1-binding protein) is a member of the polycomb group (PcG). This protein interacts with MDM2 and decreases MDM2-mediated p53 ubiquitination, leading to stabilization of p53 and an increase in p53 activity. RYBP induces cell-cycle arrest and is involved in the p53 response to DNA damage. RYBP has been shown to interact with RING1, YY1, Caspase 10, E2F3, E2F2, Mdm2, Abl gene and CBX2. Recombinant human RYBP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT, 100mM NaCl
Antigen Species
Human
Gene Category
Apoptosis
Domain
1-228aa
Species of Protein
Human
Manufacturer - Search Terms
RYBP, RING1 and YY1 binding protein, AAP1, DEDAF, YEAF1, ATGP1600-10ug, ATGP1600-20ug, ATGP1600-50ug, ATGP1600-100ug, ATGP1600-250ug, ATGP1600-500ug, ATGP1600-1mg, ATGP1600-10, ATGP1600-20, ATGP1600-50, ATGP1600-100, ATGP1600-250, ATGP1600-500, ATGP1600-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 4 ug
Available: In stock
available

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