Comparison

Recombinant human CDK4 protein

Item no. NKM-ATGP1724-500ug
Manufacturer NKMAX
Amount 500 ug
Quantity options 100 ug 20 ug 500 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 85% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MGSMATSRYE PVAEIGVGAY GTVYKARDPH SGHFVALKSV RVPNGGGGGG GLPISTVREV ALLRRLEAFE HPNVVRLMDV CATSRTDREI KVTLVFEHVD QDLRTYLDKA PPPGLPAETI KDLMRQFLRG LDFLHANCIV HRDLKPENIL VTSGGTVKLA DFGLARIYSY QMALTPVVVT LWYRAPEVLL QSTYATPVDM WSVGCIFAEM FR
Citations Serrano M., et al. (1993) Nature.366:704-707.
Kato J Y., et al. (1994) Mol Cell Biol. 14:2713-2721.
NCBI NP_000066
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Cyclin-dependent kinase 4,CMM3,PSK-J3
Similar products CDK4, Cyclin-dependent kinase 4, PSK-J3, CMM3, ATGP1724-10ug, ATGP1724-20ug, ATGP1724-50ug, ATGP1724-100ug, ATGP1724-250ug, ATGP1724-500ug, ATGP1724-1mg, ATGP1724-10, ATGP1724-20, ATGP1724-50, ATGP1724-100, ATGP1724-250, ATGP1724-500, ATGP1724-1
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Denatured
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
36.1 kDa (326aa)
Description
Cyclin-dependent kinase 4, also known as CDK4, belongs to the Cyclin-dependent kinases (CDK) family. CDK are the catalytic subunits of the cyclin/cdk complexes, which phosphorylate substrates on threonine/serine residues. CDK4, in complex with D-type cyclins, is thought to regulate cell growth during the G1 phase of the cell cycle. This association with a D-type cyclin upregulates CDK4 activity, whereas binding to the CDK inhibitor p16 downregulates CDK4 activity. Recombinant human CDK4 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Antigen Species
Human
Gene Category
Cell Cycle
Domain
1-303aa
Species of Protein
Human
Manufacturer - Search Terms
CDK4, Cyclin-dependent kinase 4, CMM3, PSK-J3, ATGP1724-10ug, ATGP1724-20ug, ATGP1724-50ug, ATGP1724-100ug, ATGP1724-250ug, ATGP1724-500ug, ATGP1724-1mg, ATGP1724-10, ATGP1724-20, ATGP1724-50, ATGP1724-100, ATGP1724-250, ATGP1724-500, ATGP1724-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 ug
Available: In stock
available

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