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Recombinant human AICDA protein

Recombinant human AICDA protein

Item no.	NKM-ATGP1895-20ug
Manufacturer	NKMAX
Amount	20 ug
Quantity options	100 ug 20 ug 500 ug
Category	Oncology By Cell Type Carcinoma Hematology Lymphoma Myeloma Peptides & Proteins Recombinant Proteins SDS-PAGE
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 85% by SDS-PAGE
Sequence	<MGSSHHHHHH SSGLVPRGSH> MDSLLMNRRK FLYQFKNVRW AKGRRETYLC YVVKRRDSAT SFSLDFGYLR NKNGCHVELL FLRYISDWDL DPGRCYRVTW FTSWSPCYDC ARHVADFLRG NPNLSLRIFT ARLYFCEDRK AEPEGLRRLH RAGVQIAIMT FKDYFYCWNT FVENHERTFK AWEGLHENSV RLSRQLRRIL LPLYEVDDLR DAFRTLGL
Citations	Guo J.u., et al. (2010) Cell. 145:423-434 Noguchi E., et al. (2001) J. Allergy Clin. 108:382-386
NCBI	NP_065712.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Activation-induced cytidine deaminase,AID,ARP2,CDA2,HIGM2
Similar products	AID, AICDA, ARP2, CDA2, HIGM2, Activation-induced cytidine deaminase, ATGP1895-10ug, ATGP1895-20ug, ATGP1895-50ug, ATGP1895-100ug, ATGP1895-250ug, ATGP1895-500ug, ATGP1895-1mg, ATGP1895-10, ATGP1895-20, ATGP1895-50, ATGP1895-100, ATGP1895-250, ATGP1895-500, ATGP1895-1
Available
Manufacturer - Type	Recombinant Protein
Manufacturer - Applications	SDS-PAGE, Denatured
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	26.1 kDa (218aa)
Description	AICDA, also known as AID, is involved in somatic hypermutation, gene conversion, and class-switch recombination in B-lymphocytes. This protein is required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. It may also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. Recombinant human AICDA protein, fused to His-tag at N-terminus, was expressed in E. coli.
Concentration	0.5mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Antigen Species	Human
Gene Category	Epigenomics (Transcription & Translation)
Domain	1-198aa
Species of Protein	Human
Manufacturer - Search Terms	AICDA, Activation-induced cytidine deaminase, AID, ARP2, CDA2, HIGM2, ATGP1895-10ug, ATGP1895-20ug, ATGP1895-50ug, ATGP1895-100ug, ATGP1895-250ug, ATGP1895-500ug, ATGP1895-1mg, ATGP1895-10, ATGP1895-20, ATGP1895-50, ATGP1895-100, ATGP1895-250, ATGP1895-500, ATGP1895-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 ug

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Delivery expected until 7/31/2025

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