Comparison

Recombinant human MVK protein

Item no. NKM-ATGP1933-500ug
Manufacturer NKMAX
Amount 500 ug
Quantity options 100 ug 20 ug 500 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH MGS>MLSEVLL VSAPGKVILH GEHAVVHGKV ALAVSLNLRT FLRLQPHSNG KVDLSLPNIG IKRAWDVARL QSLDTSFLEQ GDVTTPTSEQ VEKLKEVAGL PDDCAVTERL AVLAFLYLYL SICRKQRALP SLDIVVWSEL PPGAGLGSSA AYSVCLAAAL LTVCEEIPNP LKDGDCVNRW TKEDLELINK WAFQGERMIH GNPSGVDNAV
Citations Cuisset L., et al. (2001) Eur. J. Hum. Genet. 9:260-266
D'Osualdo A., et al. (2005) Eur. J. Hum. Genet. 13:314-320
NCBI NP_001107657.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Mevalonate kinase,LRBP,MK,MVLK
Similar products MVK, Mevalonate kinase, MK, LRBP, MVLK, ATGP1933-10ug, ATGP1933-20ug, ATGP1933-50ug, ATGP1933-100ug, ATGP1933-250ug, ATGP1933-500ug, ATGP1933-1mg, ATGP1933-10, ATGP1933-20, ATGP1933-50, ATGP1933-100, ATGP1933-250, ATGP1933-500, ATGP1933-1
Available
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
44.8 kDa (419aa) confirmed by MALDI-TOF
Description
Mevalonate kinase, also known as MVK, belongs to the GHMP kinase family. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Recombinant human MVK protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Antigen Species
Human
Gene Category
Metabolism
Domain
1-396aa
Species of Protein
Human
Manufacturer - Search Terms
MVK, Mevalonate kinase, LRBP, MK, MVLK, ATGP1933-10ug, ATGP1933-20ug, ATGP1933-50ug, ATGP1933-100ug, ATGP1933-250ug, ATGP1933-500ug, ATGP1933-1mg, ATGP1933-10, ATGP1933-20, ATGP1933-50, ATGP1933-100, ATGP1933-250, ATGP1933-500, ATGP1933-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 ug
Available: In stock
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