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Recombinant human TDP1 protein

Recombinant human TDP1 protein

Item no.	NKM-ATGP1950-500ug
Manufacturer	NKMAX
Amount	500 ug
Quantity options	100 ug 20 ug 500 ug
Category	Peptides & Proteins Recombinant Proteins SDS-PAGE Cardiovascular Research Thrombosis & Hemostasis
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 90% by SDS-PAGE
Sequence	MGSSHHHHHH SSGLVPRGSH MSQEGDYGRW TISSSDESEE EKPKPDKPST SSLLCARQGA ANEPRYTCSE AQKAAHKRKI SPVKFSNTDS VLPPKRQKSG SQEDLGWCLS SSDDELQPEM PQKQAEKVVI KKEKDISAPN DGTAQRTENH GAPACHRLKE EEDEYETSGE GQDIWDMLDK GNPFQFYLTR VSGVKPKYNS GALHIKDILS PLFGTLVSSA QFNYCFDVDW LV
Citations	Heilig R., et al. (2003) Nature. 421:601-607 The MGC Project Team. (2004) Genome Res. 14:2121-2127
NCBI	AAH06083
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Tyrosyl-DNA phosphodiesterase 1,FLJ11090,SCAN1,Tyr-DNA phosphodiesterase 1,Tyrosyl DNA phosphodiesterase 1,TDP-1
Similar products	TDP1, Tyrosyl-DNA phosphodiesterase 1, SCAN1, FLJ11090, Tyr-DNA phosphodiesterase 1, Tyrosyl DNA phosphodiesterase 1, TDP-1, ATGP1950-10ug, ATGP1950-20ug, ATGP1950-50ug, ATGP1950-100ug, ATGP1950-250ug, ATGP1950-500ug, ATGP1950-1mg, ATGP1950-10, ATGP1950-20, ATGP1950-50, ATGP1950-100, ATGP1950-250, ATGP1950-500, ATGP1950-1
Available
Manufacturer - Type	Recombinant Protein
Manufacturer - Applications	SDS-PAGE, Denatured
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	35.8 kDa (318aa)
Description	Tyrosyl-DNA phosphodiesterase 1, also known as TDP1, is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. Recombinant human TDP1, fused to His-tag at N-terminus, was expressed in E. coli.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Antigen Species	Human
Gene Category	Epigenomics (Transcription & Translation)
Domain	1-298aa
Species of Protein	Human
Manufacturer - Search Terms	TDP1, Tyrosyl-DNA phosphodiesterase 1, FLJ11090, SCAN1, Tyr-DNA phosphodiesterase 1, Tyrosyl DNA phosphodiesterase 1, TDP-1, ATGP1950-10ug, ATGP1950-20ug, ATGP1950-50ug, ATGP1950-100ug, ATGP1950-250ug, ATGP1950-500ug, ATGP1950-1mg, ATGP1950-10, ATGP1950-20, ATGP1950-50, ATGP1950-100, ATGP1950-250, ATGP1950-500, ATGP1950-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 7/31/2025

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