Comparison

Recombinant human TDP1 protein

Item no. NKM-ATGP1950-500ug
Manufacturer NKMAX
Amount 500 ug
Quantity options 100 ug 20 ug 500 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 90% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MSQEGDYGRW TISSSDESEE EKPKPDKPST SSLLCARQGA ANEPRYTCSE AQKAAHKRKI SPVKFSNTDS VLPPKRQKSG SQEDLGWCLS SSDDELQPEM PQKQAEKVVI KKEKDISAPN DGTAQRTENH GAPACHRLKE EEDEYETSGE GQDIWDMLDK GNPFQFYLTR VSGVKPKYNS GALHIKDILS PLFGTLVSSA QFNYCFDVDW LV
Citations Heilig R., et al. (2003) Nature. 421:601-607
The MGC Project Team. (2004) Genome Res. 14:2121-2127
NCBI AAH06083
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Tyrosyl-DNA phosphodiesterase 1,FLJ11090,SCAN1,Tyr-DNA phosphodiesterase 1,Tyrosyl DNA phosphodiesterase 1,TDP-1
Similar products TDP1, Tyrosyl-DNA phosphodiesterase 1, SCAN1, FLJ11090, Tyr-DNA phosphodiesterase 1, Tyrosyl DNA phosphodiesterase 1, TDP-1, ATGP1950-10ug, ATGP1950-20ug, ATGP1950-50ug, ATGP1950-100ug, ATGP1950-250ug, ATGP1950-500ug, ATGP1950-1mg, ATGP1950-10, ATGP1950-20, ATGP1950-50, ATGP1950-100, ATGP1950-250, ATGP1950-500, ATGP1950-1
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Denatured
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
35.8 kDa (318aa)
Description
Tyrosyl-DNA phosphodiesterase 1, also known as TDP1, is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. Recombinant human TDP1, fused to His-tag at N-terminus, was expressed in E. coli.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Antigen Species
Human
Gene Category
Epigenomics (Transcription & Translation)
Domain
1-298aa
Species of Protein
Human
Manufacturer - Search Terms
TDP1, Tyrosyl-DNA phosphodiesterase 1, FLJ11090, SCAN1, Tyr-DNA phosphodiesterase 1, Tyrosyl DNA phosphodiesterase 1, TDP-1, ATGP1950-10ug, ATGP1950-20ug, ATGP1950-50ug, ATGP1950-100ug, ATGP1950-250ug, ATGP1950-500ug, ATGP1950-1mg, ATGP1950-10, ATGP1950-20, ATGP1950-50, ATGP1950-100, ATGP1950-250, ATGP1950-500, ATGP1950-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 ug
Available: In stock
available

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