Comparison

Recombinant human CTLA4 protein

Item no. NKM-ATGP1959-500ug
Manufacturer NKMAX
Amount 500 ug
Quantity options 100 ug 20 ug 500 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH MGS>KAMHVAQ PAVVLASSRG IASFVCEYAS PGKATEVRVT VLRQADSQVT EVCAATYMMG NELTFLDDSI CTGTSSGNQV NLTIQGLRAM DTGLYICKVE LMYPPPYYLG IGNGTQIYVI DPEPCPDSD
Citations Rudd CE, Taylor A, et al. (2009). Immunol Rev. 229(1):12-26.
Stamper CC, Zhang Y, et al. (2001). Nature. 410(6828):608-11.
NCBI NP_005205.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM precursor,Cytotoxic T-lymphocyte-associated antigen 4,CTLA-4,CD152,CELIAC3,Celiac disease 3,Insulin-dependent diabetes mellitus 12,IDDM12,CD,GSE
Similar products ICOS, CD152, CTLA4, CD, CELIAC3, GRD4, GSE, IDDM12, Cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM precursor, ATGP1959-10ug, ATGP1959-20ug, ATGP1959-50ug, ATGP1959-100ug, ATGP1959-250ug, ATGP1959-500ug, ATGP1959-1mg, ATGP1959-10, ATGP1959-20, ATGP1959-50, ATGP1959-100, ATGP1959-250, ATGP1959-500, ATGP1959-1
Available
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Denatured
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
15.9 kDa (149aa)
Description
CTLA4 is a member of the immunoglobulin superfamily and transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. Recombinant human CTLA4 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Antigen Species
Human
Gene Category
Immunology
Domain
36-161aa
Species of Protein
Human
Manufacturer - Search Terms
CTLA4, Cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM precursor, Cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM precursor, CD, CD152, CELIAC3, GRD4, GSE, ICOS, IDDM12, ATGP1959-10ug, ATGP1959-20ug, ATGP1959-50ug, ATGP1959-100ug, ATGP1959-250ug, ATGP1959-500ug, ATGP1959-1mg, ATGP1959-10, ATGP1959-20, ATGP1959-50, ATGP1959-100, ATGP1959-250, ATGP1959-500, ATGP1959-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 ug
Available: In stock
available

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