Comparison

Recombinant human PIM1 protein

Item no. NKM-ATGP1997-100ug
Manufacturer NKMAX
Amount 100 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Category
Type Proteins
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 90% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH M>YQVGPLLGS GGFGSVYSGI RVSDNLPVAI KHVEKDRISD WGELPNGTRV PMEVVLLKKV SSGFSGVIRL LDWFERPDSF VLILERPEPV QDLFDFITER GALQEELARS FFWQVLEAVR HCHNCGVLHR DIKDENILID LNRGELKLID FGSGALLKDT VYTDFDGTRV YSPPEWIRYH RYHGRSAAVW SLGILLYDMV CGDIPFEHDE
Citations Koike N., et al. (2000) FEBS Lett. 467:17-21
Ionov Y., et al. (2003) Anticancer Res. 23:167-178
NCBI NP_002639.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Non-specific serine/threonine protein kinase,PIM
Similar products PIM1, PIM, Non-specific serine/threonine protein kinase, ATGP1997-10ug, ATGP1997-20ug, ATGP1997-50ug, ATGP1997-100ug, ATGP1997-250ug, ATGP1997-500ug, ATGP1997-1mg, ATGP1997-10, ATGP1997-20, ATGP1997-50, ATGP1997-100, ATGP1997-250, ATGP1997-500, ATGP1997-1
Available
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
31.4 kDa (274aa) confirmed by MALDI-TOF
Description
PIM1 belongs to the Ser/Thr protein kinase family, and PIM subfamily. This protein is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AuG (CuG) and downstream AuG codons. Recombinant human Pim1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Antigen Species
Human
Gene Category
Cancer
Domain
38-290aa
Species of Protein
Human
Manufacturer - Search Terms
PIM1, Non-specific serine/threonine protein kinase, PIM, ATGP1997-10ug, ATGP1997-20ug, ATGP1997-50ug, ATGP1997-100ug, ATGP1997-250ug, ATGP1997-500ug, ATGP1997-1mg, ATGP1997-10, ATGP1997-20, ATGP1997-50, ATGP1997-100, ATGP1997-250, ATGP1997-500, ATGP1997-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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