Comparison

Recombinant human Desert Hedgehog/Dhh (C23II) protein

Item no. NKM-ATGP2221-20ug
Manufacturer NKMAX
Amount 20 ug
Quantity options 100 ug 20 ug 500 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 90% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MGSMIIGPGR GPVGRRRYAR KQLVPLLYKQ FVPGVPERTL GASGPAEGRV ARGSERFRDL VPNYNPDIIF KDEENSGADR LMTERCKERV NALAIAVMNM WPGVRLRVTE GWDEDGHHAQ DSLHYEGRAL DITTSDRDRN KYGLLARLAV EAGFDWVYYE SRNHVHVSVK ADNSLAVRAG G
Citations Chen YJ, et al. (2007). Cell Cycle. 6(15):1826-30.
Van den Brink GR., et al. (2007). Physiol Rev. 87(4):1343-75
NCBI NP_066382
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Desert hedgehog protein,desert hedgehog,GDXYM,HHG-3,SRXY7
Similar products Desert hedgehog protein, HHG-3, desert hedgehog, GDXYM, SRXY7, Desert Hedgehog, Dhh (C23II), ATGP2221-10ug, ATGP2221-20ug, ATGP2221-50ug, ATGP2221-100ug, ATGP2221-250ug, ATGP2221-500ug, ATGP2221-1mg, ATGP2221-10, ATGP2221-20, ATGP2221-50, ATGP2221-100, ATGP2221-250, ATGP2221-500, ATGP2221-1
Available
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
22.4 kDa (201aa) confirmed by MALDI-TOF
Description
DHH is a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development. Recombinant human DHH protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Antigen Species
Human
Gene Category
Stem Cell
Domain
23-198aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Species of Protein
Human
Manufacturer - Search Terms
Desert Hedgehog, Dhh (C23II), Desert hedgehog protein, desert hedgehog, GDXYM, HHG-3, SRXY7, ATGP2221-10ug, ATGP2221-20ug, ATGP2221-50ug, ATGP2221-100ug, ATGP2221-250ug, ATGP2221-500ug, ATGP2221-1mg, ATGP2221-10, ATGP2221-20, ATGP2221-50, ATGP2221-100, ATGP2221-250, ATGP2221-500, ATGP2221-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 20 ug
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close