Comparison

Recombinant human CD59 protein

Item no. NKM-ATGP2258-20ug
Manufacturer NKMAX
Amount 20 ug
Quantity options 100 ug 20 ug 4 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 85% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MGSLQCYNCP NPTADCKTAV NCSSDFDACL ITKAGLQVYN KCWKFEHCNF NDVTTRLREN ELTYYCCKKD LCNFNEQLEN
Citations Ninomiya H., et al (1992). J. Biol. Chem. 267: 13675-13680
Rudd P.M., et al (1997). J. Biol. Chem. 272:7229-7244
NCBI NP_000602
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CD59 glycoprotein,16.3A5,1F5,EJ16,EJ30,EL32,G344,HRF-20,HRF20,MAC-IP,MACIF,MEM43,MIC11,MIN1,MIN2,MIN3,MIRL,MSK21,p18-20
Similar products CD59, 16.3A5, 1F5, EJ16, EJ30, EL32, G344, HRF-20, HRF20, MAC-IP, MACIF, MEM43, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20, CD59 glycoprotein, ATGP2258-10ug, ATGP2258-20ug, ATGP2258-50ug, ATGP2258-100ug, ATGP2258-250ug, ATGP2258-500ug, ATGP2258-1mg, ATGP2258-10, ATGP2258-20, ATGP2258-50, ATGP2258-100, ATGP2258-250, ATGP2258-500, ATGP2258-1
Available
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
11.3 kDa (100aa) confirmed by MALDI-TOF
Description
CD59 is a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. It also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Recombinant human CD59 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Antigen Species
Human
Gene Category
Stem Cell
Domain
26-102aa
Species of Protein
Human
Manufacturer - Search Terms
CD59, CD59 glycoprotein, 16.3A5, 1F5, EJ16, EJ30, EL32, G344, HRF-20, HRF20, MAC-IP, MACIF, MEM43, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20, ATGP2258-10ug, ATGP2258-20ug, ATGP2258-50ug, ATGP2258-100ug, ATGP2258-250ug, ATGP2258-500ug, ATGP2258-1mg, ATGP2258-10, ATGP2258-20, ATGP2258-50, ATGP2258-100, ATGP2258-250, ATGP2258-500, ATGP2258-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 20 ug
Available: In stock
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