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Recombinant human PPM1F protein

Recombinant human PPM1F protein

Item no.	NKM-ATGP2281-500ug
Manufacturer	NKMAX
Amount	500 ug
Quantity options	100 ug 20 ug 500 ug
Category	Neuroscience Molecular Targets for Neuroscience Neural Adhesion Molecules Peptides & Proteins Recombinant Proteins SDS-PAGE
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 90% by SDS-PAGE
Sequence	<MGSSHHHHHH SSGLVPRGSH MGS>MSSGAPQ KSSPMASGAE ETPGFLDTLL QDFPALLNPE DPLPWKAPGT VLSQEEVEGE LAELAMGFLG SRKAPPPLAA ALAHEAVSQL LQTDLSEFRK LPREEEEEEE DDDEEEKAPV TLLDAQSLAQ SFFNRLWEVA GQWQKQVPLA ARASQRQWLV SIHAIRNTRR KMEDRHVSLP SFNQLFGLSD PVNRAYFAVF DGHGGVDAAR
Citations	Tan KM, Chan SL, et al. (2001). J Biol Chem. 276(47):44193-202. Harvey BP, Banga SS, et al. (2004). J Biol Chem. 279(23):24889-98.
NCBI	NP_055449
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Protein phosphatase 1F,CAMKP,CaMKPase,FEM-2,hFEM-2,POPX2
Similar products	PPM1F, POPX2, Protein phosphatase 1F, CAMKP, CaMKPase, FEM-2, hFEM-2, ATGP2281-10ug, ATGP2281-20ug, ATGP2281-50ug, ATGP2281-100ug, ATGP2281-250ug, ATGP2281-500ug, ATGP2281-1mg, ATGP2281-10, ATGP2281-20, ATGP2281-50, ATGP2281-100, ATGP2281-250, ATGP2281-500, ATGP2281-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	52.2 kDa (477aa)
Description	PPM1F is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. Recombinant human PPM1F protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
Antigen Species	Human
Gene Category	Signal Transduction
Domain	1-454aa
Species of Protein	Human
Manufacturer - Search Terms	PPM1F, Protein phosphatase 1F, CAMKP, CaMKPase, FEM-2, hFEM-2, POPX2, ATGP2281-10ug, ATGP2281-20ug, ATGP2281-50ug, ATGP2281-100ug, ATGP2281-250ug, ATGP2281-500ug, ATGP2281-1mg, ATGP2281-10, ATGP2281-20, ATGP2281-50, ATGP2281-100, ATGP2281-250, ATGP2281-500, ATGP2281-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 7/31/2025

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