Comparison

Recombinant human PCBP1 protein

Item no. NKM-ATGP2314-500ug
Manufacturer NKMAX
Amount 500 ug
Quantity options 100 ug 20 ug 500 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 85% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MGSMDAGVTE SGLNVTLTIR LLMHGKEVGS IIGKKGESVK RIREESGARI NISEGNCPER IITLTGPTNA IFKAFAMIID KLEEDINSSM TNSTAASRPP VTLRLVVPAT QCGSLIGKGG CKIKEIREST GAQVQVAGDM LPNSTERAIT IAGVPQSVTE CVKQIC
Citations Beausoleil S.A., et al. (2006) Nat. Biotechnol. 24:1285-1292
Yu L.-R., et al. (2007) J. Proteome Res. 6:4150-4162
NCBI NP_006187
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Poly(rC) binding protein 1,Poly(rC) binding protein 1,hnRNP-E1,hnRNP-X,HNRPE1,HNRPX
Similar products PCBP1, HNRPE1, HNRPX, hnRNP-E1, hnRNP-X, Poly(rC) binding protein 1, ATGP2314-10ug, ATGP2314-20ug, ATGP2314-50ug, ATGP2314-100ug, ATGP2314-250ug, ATGP2314-500ug, ATGP2314-1mg, ATGP2314-10, ATGP2314-20, ATGP2314-50, ATGP2314-100, ATGP2314-250, ATGP2314-500, ATGP2314-1
Available
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
19.6 kDa (186aa) confirmed by MALDI-TOF
Description
PCBP1 appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly (rC) -binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promotes poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. PCBP1 is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. Recombinant human PCBP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
Antigen Species
Human
Gene Category
Epigenomics (Transcription & Translation)
Domain
1-163aa
Species of Protein
Human
Manufacturer - Search Terms
PCBP1, Poly(rC) binding protein 1, Poly(rC) binding protein 1, hnRNP-E1, hnRNP-X, HNRPE1, HNRPX, ATGP2314-10ug, ATGP2314-20ug, ATGP2314-50ug, ATGP2314-100ug, ATGP2314-250ug, ATGP2314-500ug, ATGP2314-1mg, ATGP2314-10, ATGP2314-20, ATGP2314-50, ATGP2314-100, ATGP2314-250, ATGP2314-500, ATGP2314-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 ug
Available: In stock
available

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