Comparison

Recombinant human TRIAP1 protein

Item no. NKM-ATGP2431-20ug
Manufacturer NKMAX
Amount 20 ug
Quantity options 100 ug 20 ug 500 ug
Category
Type Proteins Recombinant
Format Liquid
Applications SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag HIS
Purity > 90% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MGSMNSVGEA CTDMKREYDQ CFNRWFAEKF LKGDSSGDPC TDLFKRYQQC VQKAIKEKEI PIEGLEFMGH GKEKPENSS
Citations Park WR., et al. (2005) Cancer Res. 65(4): 1197-206.
Staib F., et al. (2005) Cancer Res. 65(22): 10255-64.
NCBI NP_057483
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias TP53-regulated inhibitor of apoptosis 1,HSPC132,MDM35,P53CSV,WF-1
Similar products HSPC132, P53CSV, WF-1, TRIAP1, TP53-regulated inhibitor of apoptosis 1, MDM35, ATGP2431-10ug, ATGP2431-20ug, ATGP2431-50ug, ATGP2431-100ug, ATGP2431-250ug, ATGP2431-500ug, ATGP2431-1mg, ATGP2431-10, ATGP2431-20, ATGP2431-50, ATGP2431-100, ATGP2431-250, ATGP2431-500, ATGP2431-1
Available
Manufacturer - Type
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
11.2 kDa (99aa) confirmed by MALDI-TOF
Description
TP53-regulated inhibitor of apoptosis 1, also known as TRIAP1, contains a p53-binding site within its second exon and the reduction of expression by small interfering RNA enhanced apoptosis, whereas overexpression protected cells from apoptosis caused by DNA damage. TRIAP1 is induced significantly when cells have a low level of genotoxic stresses, but not when DNA damage is severe. TRIAP1 can modulate apoptotic pathways through interaction with Hsp70 that probably inhibits activity of apoptosis protease activating factor-1. Recombinant human TRIAP1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol, 1mM DTT
Antigen Species
Human
Gene Category
Apoptosis
Domain
1-76aa
Species of Protein
Human
Manufacturer - Search Terms
TRIAP1, TP53-regulated inhibitor of apoptosis 1, HSPC132, MDM35, P53CSV, WF-1, ATGP2431-10ug, ATGP2431-20ug, ATGP2431-50ug, ATGP2431-100ug, ATGP2431-250ug, ATGP2431-500ug, ATGP2431-1mg, ATGP2431-10, ATGP2431-20, ATGP2431-50, ATGP2431-100, ATGP2431-250, ATGP2431-500, ATGP2431-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 20 ug
Available: In stock
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